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- Title
Appendix to Paper by Wall and Herbeck.
- Authors
Slatkin, Montgomery; Novembre, John
- Abstract
A method is described for determining the number of preferred codons in taxa in which G+C levels differ. If the hypothesis of random codon usage is not rejected, there are no preferred codons. If that hypothesis is rejected, then a model with one or two preferred codons is fitted to the data and a likelihood ratio test is used to determine whether there are one or two preferred codons. A C++ program is freely available to perform the calculations.
- Subjects
HYPOTHESIS; MOLECULAR biology; BIOLOGICAL evolution; MEDICAL research; BIOLOGICAL classification; AMINO acids
- Publication
Journal of Molecular Evolution, 2003, Vol 56, Issue 6, p689
- ISSN
0022-2844
- Publication type
Article
- DOI
10.1007/s00239-002-2440-z