We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Seasonal Changes in Serum Dehydroepiandrosterone, Androstenedione, and Testosterone Levels in the Squirrel Monkey (Saimiri boliviensis boliviensis).
- Authors
Wiebe, R. Herbert; Williams, Lawrence E.; Abee, Christian R.; Yeoman, Richard R.; Diamond, Edward J.
- Abstract
The squirrel monkey (Saimiri boliviensis boliviensis) has a well-defined breeding season during which adult males undergo androgen-dependent morphological changes, with acquisition of active spermatogenesis. To assess the hormonal events of this annual cycle, blood samples were obtained weekly from ten adult males, and serum was assayed for testosterone (T), androstenedione (ΔA), and dehydroepiandrosterone (DHEA). A significant seasonal variation was noted in mean serum T (P < 0.02), ΔA (P < 0.02), and DHEA (P < 0.001) concentrations. Mean &Deta;A concentrations increased from a nonbreeding season nadir of 91.4 ± 12.9 ng/ml (mean ± standard error) to a prebreeding concentration of 139 ± 10.5 ng/ml and breeding season peak of 167.5 ± 15.4 ng/ml (P < 0.05). Mean DHEA concentrations increased from a nonbreeding season nadir of 8.3 ± 0.8 to a breeding season peak of 14.3 ± 1.2 (P < 0.001). Mean T levels in the nonbreeding (52.2 ± 11.6 ng/ml) and prebreeding season (48.6 ± 7.4) were similar. However, T significantly increased during the breeding season to 103.5 ± 12.8 ng/ml (P < 0.05). Progressive changes in body weight and morphology paralleled the rise in serum &Deta;A levels. The pattern of peripheral serum androgen concentrations throughout the year would suggest annual activation of the hypothalamic-pituitary-adrenal and/or hypothalamic-pituitary-gonadal axes.
- Subjects
SQUIRREL monkeys; DEHYDROEPIANDROSTERONE; ANDROSTENEDIONE; TESTOSTERONE; SEASONAL variations in reproduction; SPERMATOGENESIS in animals; ANDROGENS
- Publication
American Journal of Primatology, 1988, Vol 14, Issue 3, p285
- ISSN
0275-2565
- Publication type
Article
- DOI
10.1002/ajp.1350140309