We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Laparoscopic cytoreductive surgery and early postoperative intraperitoneal chemotherapy for patients with colorectal cancer peritoneal carcinomatosis: initial results from a single center.
- Authors
Park, Soo; Choi, Gyu-Seog; Park, Jun; Kim, Hye; Ryuk, Jong-Pil; Yun, Sung-Hwan; Kim, Jong; Kang, Byung
- Abstract
Background: In recent decades, a combination of cytoreductive surgery and intraperitoneal chemotherapy has yielded improvements in the survival of patients with peritoneal carcinomatosis. Laparoscopic cytoreductive surgery and intraperitoneal chemotherapy comprise a challenging and rarely reported surgical procedure. Methods: Between November 2004 and February 2010, 29 patients underwent cytoreductive surgery and early postoperative intraperitoneal chemotherapy for peritoneal carcinomatosis secondary to colorectal cancer. Of the 29 patients, 15 underwent laparoscopic surgery and 14 underwent open surgery. Results: The patient characteristics did not differ significantly between the two groups. Synchronous peritoneal carcinomatosis with a primary tumor was more common in the laparoscopic group, and the Gilly stage of peritoneal carcinomatosis was found more frequently in the open group. Complication rate and hospital stay were less in the laparoscopic group. However, the outcomes for the patients undergoing the combined treatment were similar between the two groups with respect to completeness of cytoreduction, operation morbidity, and overall survival. The laparoscopic group had a cytoreduction completeness of 86.7 % and an operative morbidity of 13.3 %. Operative mortality occurred for one patient after open surgery. Conclusions: Laparoscopic cytoreductive surgery and early postoperative intraperitoneal chemotherapy can be performed safely for selected patients with peritoneal carcinomatosis from colorectal cancer to a limited extent. Further studies with longer follow-up periods and larger numbers of patients are warranted to confirm the study findings.
- Subjects
PHYSIOLOGICAL effects of chemotherapy; CARCINOMA; COLON cancer; RECTAL cancer; CYTOREDUCTIVE surgery
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2014, Vol 28, Issue 5, p1555
- ISSN
1866-6817
- Publication type
Article
- DOI
10.1007/s00464-013-3351-3