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Nonpeptidic Z360-Analogs Tagged with Trivalent Radiometals as Anti-CCK 2 R Cancer Theranostic Agents: A Preclinical Study.
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- Pharmaceutics, 2022, v. 14, n. 3, p. 666, doi. 10.3390/pharmaceutics14030666
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- Publication type:
- Article
Role of the cAMP sensor Epac as a determinant of K<sub>ATP</sub> channel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells.
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- Journal of Physiology, 2008, v. 586, n. 5, p. 1307, doi. 10.1113/jphysiol.2007.143818
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- Article
Cell physiology of cAMP sensor Epac.
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- Journal of Physiology, 2006, v. 577, n. 1, p. 5, doi. 10.1113/jphysiol.2006.119644
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- Article
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells.
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- Journal of Physiology, 2006, v. 573, n. 3, p. 595, doi. 10.1113/jphysiol.2006.107391
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- Publication type:
- Article
A cAMP and Ca<sup>2+</sup> coincidence detector in support of Ca<sup>2+</sup>-induced Ca<sup>2+</sup> release in mouse pancreatic β cells.
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- Journal of Physiology, 2005, v. 566, n. 1, p. 173, doi. 10.1113/jphysiol.2005.087510
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- Publication type:
- Article
Amplification of exocytosis by Ca<sup>2+</sup>-induced Ca<sup>2+</sup> release in INS-1 pancreatic β cells.
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- Journal of Physiology, 2003, v. 546, n. 1, p. 175, doi. 10.1113/jphysiol.2002.029959
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- Publication type:
- Article
cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca<sup>2+</sup>-induced Ca<sup>2+</sup> release in INS-1 pancreatic β-cells.
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- Journal of Physiology, 2001, v. 536, n. 2, p. 375, doi. 10.1111/j.1469-7793.2001.0375c.xd
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- Publication type:
- Article
A peptide triple agonist of GLP-1, neuropeptide Y1, and neuropeptide Y2 receptors promotes glycemic control and weight loss.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36178-1
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- Article
GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Lepr<sup>db/db</sup> mice.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-27015-y
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- Publication type:
- Article
Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation.
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- Reviews in Endocrine & Metabolic Disorders, 2020, v. 21, n. 4, p. 431, doi. 10.1007/s11154-020-09584-3
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- Publication type:
- Article
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like...
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- Nature, 1993, v. 361, n. 6410, p. 362, doi. 10.1038/361362a0
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- Article
Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy.
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- Scientific Reports, 2016, p. 28934, doi. 10.1038/srep28934
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- Publication type:
- Article
The alpha‐7 nicotinic acetylcholine receptor agonist GTS‐21 engages the glucagon‐like peptide‐1 incretin hormone axis to lower levels of blood glucose in db/db mice.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 7, p. 1255, doi. 10.1111/dom.14693
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- Publication type:
- Article
Cover Image, Volume 20, Issue 5.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. i, doi. 10.1111/dom.13540
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- Article
Cover Image, Volume 20, Issue 5.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. i, doi. 10.1111/dom.13314
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- Publication type:
- Article
A vitamin B12 conjugate of exendin‐4 improves glucose tolerance without associated nausea or hypophagia in rodents.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. 1223, doi. 10.1111/dom.13222
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- Publication type:
- Article
Glucagon-Like Peptide-1 Induced Signaling and Insulin Secretion Do Not Drive Fuel and Energy MetaBolism in Primary Rodent Pancreatic β-Cells.
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- PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006221
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- Publication type:
- Article
Signal Transduction of PACAP and GLP-1 in Pancreatic β Cells<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1996, v. 805, n. 1, p. 81, doi. 10.1111/j.1749-6632.1996.tb17475.x
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- Publication type:
- Article
Cyclic AMP‐dependent activation of ERK via GLP‐1 receptor signalling requires the neuroendocrine cell‐specific guanine nucleotide exchanger NCS‐RapGEF2.
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- Journal of Neuroendocrinology, 2021, v. 33, n. 7, p. 1, doi. 10.1111/jne.12974
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- Article
Cytotoxic Activity of Novel GnRH Analogs Conjugated with Mitoxantrone in Ovarian Cancer Cells.
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- Molecules, 2024, v. 29, n. 17, p. 4127, doi. 10.3390/molecules29174127
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- Article
Discovery of a stable tripeptide targeting the N-domain of CRF1 receptor.
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- Amino Acids, 2020, v. 52, n. 9, p. 1337, doi. 10.1007/s00726-020-02895-4
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- Publication type:
- Article
Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell.
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- 2004
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- Publication type:
- journal article
Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.
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- 2000
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- Publication type:
- journal article
Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells.
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- 1997
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- Publication type:
- journal article
Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic β-cell lines for use in transplantation.
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- Cell & Tissue Research, 2002, v. 307, n. 2, p. 191, doi. 10.1007/s00441-001-0494-7
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- Publication type:
- Article
Epac2-dependent mobilization of intracellular Ca.
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- Journal of Physiology, 2010, v. 588, n. 24, p. 4871, doi. 10.1113/jphysiol.2010.198424
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- Article
Observations on the Ultrastructure of Uronema spp., Marine Scuticociliates.
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- Journal of Eukaryotic Microbiology, 1976, v. 23, n. 4, p. 503, doi. 10.1111/j.1550-7408.1976.tb03829.x
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- Article
The Polyunsaturated Fatty Acids of Marine and Freshwater Cryptomonads.
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- Journal of Eukaryotic Microbiology, 1970, v. 17, n. 3, p. 501, doi. 10.1111/j.1550-7408.1970.tb04718.x
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- Article
The Polyunsaturated Fatty Acids of Marine Dinoflagellates.
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- Journal of Eukaryotic Microbiology, 1970, v. 17, n. 2, p. 213, doi. 10.1111/j.1550-7408.1970.tb02359.x
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- Article
Production of a Vitamin B<sub>12</sub> Compound by Tetrahymenids.
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- Journal of Eukaryotic Microbiology, 1962, v. 9, n. 2, p. 211, doi. 10.1111/j.1550-7408.1962.tb02608.x
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- Article
The Sterol Requirement of Tetrahymena paravorax RP.
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- Journal of Eukaryotic Microbiology, 1961, v. 8, n. 3, p. 297, doi. 10.1111/j.1550-7408.1961.tb01221.x
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- Article
Some Physiological Characteristics of the Mating Types and Varieties of Tetrahymena pyriformis.
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- Journal of Eukaryotic Microbiology, 1959, v. 6, n. 2, p. 149, doi. 10.1111/j.1550-7408.1959.tb03942.x
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- Article
Tetrahymena setifera n.sp., a Member of the Genus Tetrahymena with a Caudal Cilium.
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- Journal of Eukaryotic Microbiology, 1956, v. 3, n. 3, p. 112, doi. 10.1111/j.1550-7408.1956.tb02443.x
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- Article
The Oxidative Metabolism of a Cryptomonad Flagellate, Chilomonas paramecium.
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- Journal of Eukaryotic Microbiology, 1954, v. 1, n. 2, p. 114, doi. 10.1111/j.1550-7408.1954.tb00803.x
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- Article
Solution Structure and Constrained Molecular Dynamics Study of Vitamin B<sub>12</sub> Conjugates of the Anorectic Peptide PYY(3-36).
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- ChemMedChem, 2016, v. 11, n. 9, p. 1015, doi. 10.1002/cmdc.201600073
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- Publication type:
- Article
Synthesis, Characterization and Pharmacodynamics of Vitamin-B<sub>12</sub>-Conjugated Glucagon-Like Peptide-1.
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- ChemMedChem, 2013, v. 8, n. 4, p. 582, doi. 10.1002/cmdc.201200461
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- Publication type:
- Article
Back Cover: Synthesis, Characterization and Pharmacodynamics of Vitamin-B<sub>12</sub>-Conjugated Glucagon-Like Peptide-1 (ChemMedChem 4/2013).
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- ChemMedChem, 2013, v. 8, n. 4, p. 800, doi. 10.1002/cmdc.201390014
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- Publication type:
- Article
Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets.
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- 2018
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- Publication type:
- journal article
Epac2A Makes a New Impact in β-Cell Biology.
- Published in:
- 2013
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- Publication type:
- Opinion