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- Title
Localized pleural malignant mesothelioma.
- Authors
Hiroshi Hirano; Shinichi Takeda; Yoshinori Sawabata, Tatsuo; Yoshitomo Okumura; Hajime Maeda; Masaki Hanibuchi, Tatsuo; Masami Ito; Masaru Nakagawa, Tatsuo; Kunio Uematsu
- Abstract
The occurrence of pleural malignant mesothelioma (MM) is unusual and the cases that appear as a localized tumor are extremely rare. A case of localized pleural MM including immunohistochemical findings is presented. A 70-year-old man had an abnormal shadow found during a routine roentgenogram at an annual health checkup and was admitted to Toneyama National Hospital (Toyonaka, Osaka, Japan) for detailed examinations. Chest X-rays showed a 2 × 5 cm-sized nodule with relatively smooth margins in the right segment three. Computed tomography (CT) showed an extrapleural mass with a smooth surface and a thickened parietal pleura, and results of a biopsy performed under CT scanning yielded MM. Systematic examinations did not show any metastasis and the patient underwent surgery for removal of the mass. The resected tumor, measuring 3.2 × 3.1 cm, was firm, partially encapsulated, and irregularly shaped. Pathological examinations revealed that it consisted of large polygonal cells, partially showing myxoid patterns, which led to a diagnosis of localized pleural MM. Tumor recurrence was seen, and the duration between initial symptoms and death was 29 months. This case suggests that localized pleural MM has a high proliferative potential and aggressive course, and is considered an early stage of diffuse pleural MM.
- Subjects
MESOTHELIOMA; X-rays; TOMOGRAPHY; BIOPSY
- Publication
Pathology International, 2003, Vol 53, Issue 9, p616
- ISSN
1320-5463
- Publication type
Article
- DOI
10.1046/j.1440-1827.2003.01529.x