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Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6545, doi. 10.3390/ijms24076545
By:
- Park, Jeong-Min;
- Zhang, Huimin;
- Nie, Litong;
- Wang, Chao;
- Huang, Min;
- Feng, Xu;
- Tang, Mengfan;
- Chen, Zhen;
- Xiong, Yun;
- Lee, Namsoo;
- Li, Siting;
- Yin, Ling;
- Hart, Traver;
- Chen, Junjie
Publication type:
Article
Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance.
Published in:
Nature Communications, 2021, v. 12, p. 1, doi. 10.1038/s41467-021-24298-z
By:
- Hang, Qinglei;
- Zeng, Liyong;
- Wang, Li;
- Nie, Litong;
- Yao, Fan;
- Teng, Hongqi;
- Deng, Yalan;
- Yap, Shannon;
- Sun, Yutong;
- Frank, Steven J.;
- Chen, Junjie;
- Ma, Li
Publication type:
Article
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21841-w
By:
- Yilei Zhang;
- Swanda, Robert V.;
- Litong Nie;
- Xiaoguang Liu;
- Chao Wang;
- Hyemin Lee;
- Guang Lei;
- Chao Mao;
- Koppula, Pranavi;
- Weijie Cheng;
- Jie Zhang;
- Zhenna Xiao;
- Li Zhuang;
- Bingliang Fang;
- Junjie Chen;
- Shu-Bing Qian;
- Boyi Gan
Publication type:
Article
Interactomes of SARS‐CoV‐2 and human coronaviruses reveal host factors potentially affecting pathogenesis.
Published in:
EMBO Journal, 2021, v. 40, n. 17, p. 1, doi. 10.15252/embj.2021107776
By:
- Chen, Zhen;
- Wang, Chao;
- Feng, Xu;
- Nie, Litong;
- Tang, Mengfan;
- Zhang, Huimin;
- Xiong, Yun;
- Swisher, Samuel K;
- Srivastava, Mrinal;
- Chen, Junjie
Publication type:
Article
ATR inhibition potentiates ionizing radiation‐induced interferon response via cytosolic nucleic acid‐sensing pathways.
Published in:
EMBO Journal, 2020, v. 39, n. 14, p. 1, doi. 10.15252/embj.2019104036
By:
- Feng, Xu;
- Tubbs, Anthony;
- Zhang, Chunchao;
- Tang, Mengfan;
- Sridharan, Sriram;
- Wang, Chao;
- Jiang, Dadi;
- Su, Dan;
- Zhang, Huimin;
- Chen, Zhen;
- Nie, Litong;
- Xiong, Yun;
- Huang, Min;
- Nussenzweig, André;
- Chen, Junjie
Publication type:
Article
Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.
Published in:
Journal of Molecular Cell Biology, 2016, v. 8, n. 4, p. 349, doi. 10.1093/jmcb/mjv060
By:
- Yuichi Morozumi;
- Boussouar, Fayçal;
- Minjia Tan;
- Chaikuad, Apirat;
- Jamshidikia, Mahya;
- Colak, Gozde;
- Huang He;
- Litong Nie;
- Petosa, Carlo;
- de Dieuleveult, Maud;
- Curtet, Sandrine;
- Vitte, Anne-Laure;
- Rabatel, Clothilde;
- Debernardi, Alexandra;
- Cosset, François-Loïc;
- Verhoeyen, Els;
- Emadali, Anouk;
- Schweifer, Norbert;
- Gianni, Davide;
- Gut, Marta
Publication type:
Article
HMCES safeguards replication from oxidative stress and ensures error‐free repair.
Published in:
EMBO Reports, 2020, v. 21, n. 6, p. 1, doi. 10.15252/embr.201949123
By:
- Srivastava, Mrinal;
- Su, Dan;
- Zhang, Huimin;
- Chen, Zhen;
- Tang, Mengfan;
- Nie, Litong;
- Chen, Junjie
Publication type:
Article
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain.
Published in:
International Journal of Molecular Medicine, 2020, v. 46, n. 6, p. 2137, doi. 10.3892/ijmm.2020.4745
By:
- Pan, Lijia;
- Nie, Litong;
- Yao, Sheng;
- Bi, Aiwei;
- Ye, Yang;
- Wu, Yeming;
- Tan, Zhen;
- Wu, Zhixiang
Publication type:
Article
DePARylation is critical for S phase progression and cell survival.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.89303
By:
- Litong Nie;
- Chao Wang;
- Min Huang;
- Xiaoguang Liu;
- Xu Feng;
- Mengfan Tang;
- Siting Li;
- Qinglei Hang;
- Hongqi Teng;
- Xi Shen;
- Li Ma;
- Boyi Gan;
- Junjie Chen
Publication type:
Article
Genetic vulnerabilities upon inhibition of DNA damage response.
Published in:
Nucleic Acids Research, 2021, v. 49, n. 14, p. 8214, doi. 10.1093/nar/gkab643
By:
- Wang, Chao;
- Tang, Mengfan;
- Chen, Zhen;
- Nie, Litong;
- Li, Siting;
- Xiong, Yun;
- Szymonowicz, Klaudia Anna;
- Park, Jeong-Min;
- Zhang, Huimin;
- Feng, Xu;
- Huang, Min;
- Su, Dan;
- Hart, Traver;
- Chen, Junjie
Publication type:
Article
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis.
Published in:
Protein & Cell, 2024, v. 15, n. 9, p. 686, doi. 10.1093/procel/pwae004
By:
- Liu, Xiaoguang;
- Chen, Zhen;
- Yan, Yuelong;
- Zandkarimi, Fereshteh;
- Nie, Litong;
- Li, Qidong;
- Horbath, Amber;
- Olszewski, Kellen;
- Kondiparthi, Lavanya;
- Mao, Chao;
- Lee, Hyemin;
- Zhuang, Li;
- Poyurovsky, Masha;
- Stockwell, Brent R;
- Chen, Junjie;
- Gan, Boyi
Publication type:
Article
Beyond proteins: Ubiquitylation of lipopolysaccharide to fight bacteria.
Published in:
MedComm, 2021, v. 2, n. 4, p. 855, doi. 10.1002/mco2.86
By:
- Yanqiu Gong;
- Litong Nie;
- Lunzhi Dai
Publication type:
Article
Lysosomal TMEM9‐LAMTOR4‐controlled mTOR signaling integrity is required for mammary tumorigenesis.
Published in:
Cancer Communications, 2023, v. 43, n. 1, p. 159, doi. 10.1002/cac2.12382
By:
- Zhang, Shengzhe;
- Lee, Sung Ho;
- Nie, Litong;
- Huang, Yuanjian;
- Zou, Gengyi;
- Jung, Youn‐Sang;
- Jun, Sohee;
- Zhang, Jie;
- Lien, Esther M.;
- Chen, Junjie;
- Park, Jae‐Il
Publication type:
Article
Extracellular signal-regulated kinases associate with and phosphorylate DHPS to promote cell proliferation.
Published in:
Oncogenesis, 2020, v. 9, n. 9, p. 1, doi. 10.1038/s41389-020-00271-1
By:
- Wang, Chao;
- Chen, Zhen;
- Nie, Litong;
- Tang, Mengfan;
- Feng, Xu;
- Su, Dan;
- Zhang, Huimin;
- Xiong, Yun;
- Park, Jeong-Min;
- Chen, Junjie
Publication type:
Article

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