We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Clinical utility of metabolic syndrome severity scores: considerations for practitioners.
- Authors
DeBoer, Mark D.; Gurka, Matthew J.
- Abstract
The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetSrelated risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time.
- Subjects
METABOLIC syndrome diagnosis; INSULIN resistance; CARDIOVASCULAR diseases; TYPE 2 diabetes; FAT cells
- Publication
Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2017, Vol 10, p65
- ISSN
1178-7007
- Publication type
Article
- DOI
10.2147/DMSO.S101624