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Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion.
Published in:
Science Signaling, 2017, v. 10, n. 469, p. 1, doi. 10.1126/scisignal.aal2464
By:
- Ruggiero, Carmen;
- Doghman-Bouguerra, Mabrouka;
- Sbiera, Silviu;
- Sbiera, Iuliu;
- Parsons, Maddy;
- Ragazzon, Bruno;
- Morin, Aurélie;
- Robidel, Estelle;
- Favier, Judith;
- Bertherat, Jérôme;
- Fassnacht, Martin;
- Lalli, Enzo
Publication type:
Article
Assessment of VAV2 Expression Refines Prognostic Prediction in Adrenocortical Carcinoma.
Published in:
2017
By:
- Sbiera, Silviu;
- Sbiera, Iuliu;
- Ruggiero, Carmen;
- Doghman-Bouguerra, Mabrouka;
- Korpershoek, Esther;
- de Krijger, Ronald R;
- Ettaieb, Hester;
- Haak, Harm;
- Volante, Marco;
- Papotti, Mauro;
- Reimondo, Giuseppe;
- Terzolo, Massimo;
- Luconi, Michaela;
- Nesi, Gabriella;
- Mannelli, Massimo;
- Libé, Rossella;
- Ragazzon, Bruno;
- Assié, Guillaume;
- Bertherat, Jérôme;
- Altieri, Barbara
Publication type:
journal article
Primary Aldosteronism and ARMC5 Variants.
Published in:
2015
By:
- Zilbermint, Mihail;
- Xekouki, Paraskevi;
- Faucz, Fabio R;
- Berthon, Annabel;
- Gkourogianni, Alexandra;
- Schernthaner-Reiter, Marie Helene;
- Batsis, Maria;
- Sinaii, Ninet;
- Quezado, Martha M;
- Merino, Maria;
- Hodes, Aaron;
- Abraham, Smita B;
- Libé, Rossella;
- Assié, Guillaume;
- Espiard, Stéphanie;
- Drougat, Ludivine;
- Ragazzon, Bruno;
- Davis, Adam;
- Gebreab, Samson Y;
- Neff, Ryan
Publication type:
journal article
Macronodular adrenal hyperplasia due to mutations in an armadillo repeat containing 5 (ARMC5) gene: a clinical and genetic investigation.
Published in:
2014
By:
- Faucz, Fabio R;
- Zilbermint, Mihail;
- Lodish, Maya B;
- Szarek, Eva;
- Trivellin, Giampaolo;
- Sinaii, Ninet;
- Berthon, Annabel;
- Libé, Rossella;
- Assié, Guillaume;
- Espiard, Stéphanie;
- Drougat, Ludivine;
- Ragazzon, Bruno;
- Bertherat, Jerome;
- Stratakis, Constantine A
Publication type:
journal article
Identification of gene expression profiles associated with cortisol secretion in adrenocortical adenomas.
Published in:
2013
By:
- Wilmot Roussel, Hortense;
- Vezzosi, Delphine;
- Rizk-Rabin, Marthe;
- Barreau, Olivia;
- Ragazzon, Bruno;
- René-Corail, Fernande;
- de Reynies, Aurélien;
- Bertherat, Jérôme;
- Assié, Guillaume
Publication type:
Journal Article
Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors.
Published in:
2012
By:
- Vezzosi D;
- Libé R;
- Baudry C;
- Rizk-Rabin M;
- Horvath A;
- Levy I;
- René-Corail F;
- Ragazzon B;
- Stratakis CA;
- Vandecasteele G;
- Bertherat J;
- Vezzosi, Delphine;
- Libé, Rossella;
- Baudry, Camille;
- Rizk-Rabin, Marthe;
- Horvath, Anelia;
- Levy, Isaac;
- René-Corail, Fernande;
- Ragazzon, Bruno;
- Stratakis, Constantine A
Publication type:
journal article
A concomitant false-negative ¹⁸F-FDG PET imaging in an adrenocortical carcinoma and a high uptake in a corresponding liver metastasis.
Published in:
2012
By:
- Ghander C;
- Tissier F;
- Tenenbaum F;
- Silvera S;
- Ragazzon B;
- Bertherat J;
- Bertagna X;
- Dousset B;
- Richard B;
- Legmann P;
- Groussin L;
- Ghander, Cécile;
- Tissier, Frédérique;
- Tenenbaum, Florence;
- Silvera, Stéphane;
- Ragazzon, Bruno;
- Bertherat, Jérôme;
- Bertagna, Xavier;
- Dousset, Bertrand;
- Richard, Bruno
Publication type:
journal article
Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association.
Published in:
2011
By:
- Gaujoux, Sébastien;
- Tissier, Frédérique;
- Ragazzon, Bruno;
- Rebours, Vinciane;
- Saloustros, Emmanouil;
- Perlemoine, Karine;
- Vincent-Dejean, Caroline;
- Meurette, Guillaume;
- Cassagnau, Elisabeth;
- Dousset, Bertrand;
- Bertagna, Xavier;
- Horvath, Anelia;
- Terris, Benoit;
- Carney, J Aidan;
- Stratakis, Constantine A;
- Bertherat, Jérôme
Publication type:
journal article
Wnt/β-Catenin Pathway Activation in Adrenocortical Adenomas Is Frequently due to Somatic CTNNB1-Activating Mutations, Which Are Associated with Larger and Nonsecreting Tumors: A Study in Cortisol-Secreting and -Nonsecreting Tumors
Published in:
Journal of Clinical Endocrinology & Metabolism, 2011, v. 96, n. 2, p. 419E, doi. 10.1210/jc.2010-1885
By:
- Bonnet, Stéphane;
- Gaujoux, Sébastien;
- Launay, Pierre;
- Baudry, Camille;
- Chokri, Ilham;
- Ragazzon, Bruno;
- Libé, Rossella;
- René-Corail, Fernande;
- Audebourg, Anne;
- Vacher-Lavenu, Marie-Cécile;
- Groussin, Lionel;
- Bertagna, Xavier;
- Dousset, Bertrand;
- Bertherat, Jérôme;
- Tissier, Frédérique
Publication type:
Article
Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2011, v. 96, n. 1, p. E208, doi. 10.1210/jc.2010-1704
By:
- Libé, Rossella;
- Horvath, Anelia;
- Vezzosi, Delphine;
- Fratticci, Amato;
- Coste, Joel;
- Perlemoine, Karine;
- Ragazzon, Bruno;
- Guillaud-Bataille, Marine;
- Groussin, Lionel;
- Clauser, Eric;
- Raffin-Sanson, Marie-Laure;
- Siegel, Jennifer;
- Moran, Jason;
- Drori-Herishanu, Limor;
- Rueda Faucz, Fabio;
- Lodish, Maya;
- Nesterova, Maria;
- Bertagna, Xavier;
- Bertherat, Jerome;
- Stratakis, Constantine A.
Publication type:
Article
IGF2 Promotes Growth of Adrenocortical Carcinoma Cells, but Its Overexpression Does Not Modify Phenotypic and Molecular Features of Adrenocortical Carcinoma.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103744
By:
- Guillaud-Bataille, Marine;
- Ragazzon, Bruno;
- de Reyniès, Aurélien;
- Chevalier, Claire;
- Francillard, Isabelle;
- Barreau, Olivia;
- Steunou, Virginie;
- Guillemot, Johann;
- Tissier, Frédérique;
- Rizk-Rabin, Marthe;
- René-Corail, Fernande;
- Ghuzlan, Abir Al;
- Assié, Guillaume;
- Bertagna, Xavier;
- Baudin, Eric;
- Le Bouc, Yves;
- Bertherat, Jérôme;
- Clauser, Eric
Publication type:
Article
Silencing Mutated <i>β-Catenin</i> Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055743
By:
- Gaujoux, Sébastien;
- Hantel, Constanze;
- Launay, Pierre;
- Bonnet, Stéphane;
- Perlemoine, Karine;
- Lefèvre, Lucile;
- Guillaud-Bataille, Marine;
- Beuschlein, Felix;
- Tissier, Frédérique;
- Bertherat, Jérôme;
- Rizk-Rabin, Marthe;
- Ragazzon, Bruno
Publication type:
Article
Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0044171
By:
- Drelon, Coralie;
- Berthon, Annabel;
- Ragazzon, Bruno;
- Tissier, Frédérique;
- Bandiera, Roberto;
- Sahut-Barnola, Isabelle;
- de Joussineau, Cyrille;
- Batisse-Lignier, Marie;
- Lefrançois-Martinez, Anne-Marie;
- Bertherat, Jérôme;
- Martinez, Antoine;
- Val, Pierre;
- Culig, Zoran
Publication type:
Article
Aldo Keto Reductase 1B7 and Prostaglandin F<sub>2α</sub> Are Regulators of Adrenal Endocrine Functions.
Published in:
PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007309
By:
- Lambert-Langlais, Sarah;
- Pointud, Jean-Christophe;
- Lefrançois-Martinez, Anne-Marie;
- Volat, Fanny;
- Manin, Michèle;
- Coudoré, François;
- Val, Pierre;
- Sahut-Barnola, Isabelle;
- Ragazzon, Bruno;
- Louiset, Estelle;
- Delarue, Catherine;
- Lefebvre, Hervé;
- Urade, Yoshihiro;
- Martinez, Antoine
Publication type:
Article
High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 10, p. E161, doi. 10.1210/jc.2010-0653
By:
- Sbiera, Silviu;
- Schmull, Sebastian;
- Assie, Guillaume;
- Voelker, Hans-Ullrich;
- Kraus, Luitgard;
- Beyer, Melanie;
- Ragazzon, Bruno;
- Beuschlein, Felix;
- Willenberg, Holger S.;
- Hahner, Stefanie;
- Saeger, Wolfgang;
- Bertherat, Jerome;
- Allolio, Bruno;
- Fassnacht, Martin
Publication type:
Article
Wnt/β-Catenin and 3 ′,5 ′-Cyclic Adenosine 5 ′-Monophosphate/Protein Kinase A Signaling Pathways Alterations and Somatic β-Catenin Gene Mutations in the Progression of Adrenocortical Tumors.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 10, p. 4135, doi. 10.1210/jc.2008-0631
By:
- Gaujoux, Sébastien;
- Tissier, Frédérique;
- Groussin, Lionel;
- Libé, Rossella;
- Ragazzon, Bruno;
- Launay, Pierre;
- Audebourg, Anne;
- Dousset, Bertrand;
- Bertagna, Xavier;
- Bertherat, Jérôme
Publication type:
Article
PRKAR1A mutations in primary pigmented nodular adrenocortical disease.
Published in:
Pituitary, 2006, v. 9, n. 3, p. 211, doi. 10.1007/s11102-006-0266-1
By:
- Cazabat, Laure;
- Ragazzon, Bruno;
- Groussin, Lionel;
- Bertherat, Jérôme
Publication type:
Article
Transcriptome in paraffin samples for the diagnosis and prognosis of adrenocortical carcinoma.
Published in:
European Journal of Endocrinology, 2022, v. 186, n. 6, p. 607, doi. 10.1530/eje-21-1228
By:
- Jouinot, Anne;
- Lippert, Juliane;
- Sibony, Mathilde;
- Violon, Florian;
- Jeanpierre, Lindsay;
- Murat, Daniel De;
- Armignacco, Roberta;
- Septier, Amandine;
- Perlemoine, Karine;
- Letourneur, Franck;
- Izac, Brigitte;
- Ragazzon, Bruno;
- Leroy, Karen;
- Pasmant, Eric;
- North, Marie-Odile;
- Gaujoux, Sébastien;
- Dousset, Bertrand;
- Groussin, Lionel;
- Libe, Rossella;
- Terris, Benoit
Publication type:
Article
Mass-array screening of frequent mutations in cancers reveals RB1 alterations in aggressive adrenocortical carcinomas.
Published in:
European Journal of Endocrinology, 2014, v. 170, n. 3, p. 385, doi. 10.1530/EJE-13-0778
By:
- Ragazzon, Bruno;
- Libé, Rossella;
- Assié, Guillaume;
- Tissier, Frédérique;
- Barreau, Olivia;
- Houdayer, Claude;
- Perlemoine, Karine;
- Audebourg, Anne;
- Clauser, Eric;
- René-Corail, Fernande;
- Bertagna, Xavier;
- Dousset, Bertrand;
- Bertherat, Jérôme;
- Groussin, Lionel
Publication type:
Article
Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex.
Published in:
FASEB Journal, 2019, v. 33, n. 9, p. 10218, doi. 10.1096/fj.201900557R
By:
- Dumontet, Typhanie;
- Sahut-Barnola, Isabelle;
- Dufour, Damien;
- Lefrançois-Martinez, Anne-Marie;
- Berthon, Annabel;
- Montanier, Nathanaëlle;
- Ragazzon, Bruno;
- Djari, Cyril;
- Pointud, Jean-Christophe;
- Roucher-Boulez, Florence;
- Batisse-Lignier, Marie;
- Tauveron, Igor;
- Bertherat, Jérôme;
- Val, Pierre;
- Martinez, Antoine
Publication type:
Article
EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness.
Published in:
2019
By:
- Tabbal, Houda;
- Septier, Amandine;
- Mathieu, Mickael;
- Drelon, Coralie;
- Rodriguez, Stéphanie;
- Djari, Cyril;
- Batisse-Lignier, Marie;
- Tauveron, Igor;
- Pointud, Jean-Christophe;
- Sahut-Barnola, Isabelle;
- Ragazzon, Bruno;
- Assié, Guillaume;
- Bertherat, Jérôme;
- Lefrançois-Martinez, Anne-Marie;
- Martinez, Antoine;
- Val, Pierre
Publication type:
journal article
EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 13, p. 2789, doi. 10.1093/hmg/ddw136
By:
- Drelon, Coralie;
- Berthon, Annabel;
- Mathieu, Mickael;
- Ragazzon, Bruno;
- Kuick, Rork;
- Tabbal, Houda;
- Septier, Amandine;
- Rodriguez, Stéphanie;
- Batisse-Lignier, Marie;
- Sahut-Barnola, Isabelle;
- Dumontet, Typhanie;
- Pointud, Jean-Christophe;
- Lefrançois-Martinez, Anne-Marie;
- Baron, Silvère;
- Giordano, Thomas J.;
- Bertherat, Jérôme;
- Martinez, Antoine;
- Val, Pierre
Publication type:
Article
Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 5, p. 1163, doi. 10.1093/hmg/ddt510
By:
- Cazabat, Laure;
- Ragazzon, Bruno;
- Varin, Audrey;
- Potier-Cartereau, Marie;
- Vandier, Christophe;
- Vezzosi, Delphine;
- Risk-Rabin, Marthe;
- Guellich, Aziz;
- Schittl, Julia;
- Lechêne, Patrick;
- Richter, Wito;
- Nikolaev, Viacheslav O.;
- Zhang, Jin;
- Bertherat, Jérôme;
- Vandecasteele, Grégoire
Publication type:
Article
WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 4, p. 889, doi. 10.1093/hmg/ddt484
By:
- Berthon, Annabel;
- Drelon, Coralie;
- Ragazzon, Bruno;
- Boulkroun, Sheerazed;
- Tissier, Frédérique;
- Amar, Laurence;
- Samson-Couterie, Benoît;
- Zennaro, Maria-Christina;
- Plouin, Pierre-François;
- Skah, Seham;
- Plateroti, Michelina;
- Lefèbvre, Hervé;
- Sahut-Barnola, Isabelle;
- Batisse-Lignier, Marie;
- Assié, Guillaume;
- Lefrançois-Martinez, Anne-Marie;
- Bertherat, Jérôme;
- Martinez, Antoine;
- Val, Pierre
Publication type:
Article
Fascin-1 Is a Novel Prognostic Biomarker Associated With Tumor Invasiveness in Adrenocortical Carcinoma.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2019, v. 104, n. 5, p. 1712, doi. 10.1210/jc.2018-01717
By:
- Poli, Giada;
- Ruggiero, Carmen;
- Cantini, Giulia;
- Canu, Letizia;
- Baroni, Gianna;
- Armignacco, Roberta;
- Jouinot, Anne;
- Santi, Raffaella;
- Ercolino, Tonino;
- Ragazzon, Bruno;
- Assie, Guillaume;
- Mannelli, Massimo;
- Nesi, Gabriella;
- Lalli, Enzo;
- Luconi, Michaela
Publication type:
Article
Fascin-1 Is a Novel Prognostic Biomarker Associated With Tumor Invasiveness in Adrenocortical Carcinoma.
Published in:
2018
By:
- Poli, Giada;
- Ruggiero, Carmen;
- Cantini, Giulia;
- Canu, Letizia;
- Baroni, Gianna;
- Armignacco, Roberta;
- Jouinot, Anne;
- Santi, Raffaella;
- Ercolino, Tonino;
- Ragazzon, Bruno;
- Assie, Guillaume;
- Mannelli, Massimo;
- Nesi, Gabriella;
- Lalli, Enzo;
- Luconi, Michaela
Publication type:
journal article
Cushing's Syndrome and Fetal Features Resurgence in Adrenal Cortex-Specific Prkar1a Knockout Mice.
Published in:
PLoS Genetics, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pgen.1000980
By:
- Sahut-Barnola, Isabelle;
- de Joussineau, Cyrille;
- Val, Pierre;
- Lambert-Langlais, Sarah;
- Damon, Christelle;
- Lefrançois-Martinez, Anne-Marie;
- Pointud, Jean-Christophe;
- Marceau, Geoffroy;
- Sapin, Vincent;
- Tissier, Frédérique;
- Ragazzon, Bruno;
- Bertherat, Jérôme;
- Kirschner, Lawrence S.;
- Stratakis, Constantine A.;
- Martinez, Antoine
Publication type:
Article
Somatic Molecular Heterogeneity in Bilateral Macronodular Adrenocortical Disease (BMAD) Differs Among the Pathological Subgroups.
Published in:
Endocrine Pathology, 2024, v. 35, n. 3, p. 194, doi. 10.1007/s12022-024-09824-1
By:
- Violon, Florian;
- Bouys, Lucas;
- Vaduva, Patricia;
- Chansavang, Albain;
- Vaquier, Louis;
- Letourneur, Franck;
- Izac, Brigitte;
- Giannone, Gaëtan;
- De Murat, Daniel;
- Gaillard, Martin;
- Berthon, Annabel;
- Ragazzon, Bruno;
- Pasmant, Eric;
- Sibony, Mathilde;
- Bertherat, Jérôme
Publication type:
Article
Impact of Morphology in the Genotype and Phenotype Correlation of Bilateral Macronodular Adrenocortical Disease (BMAD): A Series of Clinicopathologically Well-Characterized 35 Cases.
Published in:
Endocrine Pathology, 2023, v. 34, n. 2, p. 179, doi. 10.1007/s12022-023-09751-7
By:
- Violon, Florian;
- Bouys, Lucas;
- Berthon, Annabel;
- Ragazzon, Bruno;
- Barat, Maxime;
- Perlemoine, Karine;
- Guignat, Laurence;
- Terris, Benoit;
- Bertherat, Jérôme;
- Sibony, Mathilde
Publication type:
Article
Novel insights into the genetics and pathophysiology of adrenocortical tumors.
Published in:
Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00096
By:
- Drougat, Ludivine;
- Omeiri, Hanin;
- Lefèvre, Lucile;
- Ragazzon, Bruno
Publication type:
Article
A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.
Published in:
2015
By:
- Canal, Frédéric;
- Anthony, Elodie;
- Lescure, Aurianne;
- Del Nery, Elaine;
- Camonis, Jacques;
- Perez, Franck;
- Ragazzon, Bruno;
- Perret, Christine
Publication type:
journal article

Found: 31