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- Title
Obesity is not associated with hip failure in patients with articular surface replacement of the hip.
- Authors
Ray, Gabrielle S; Laaksonen, Inari; Galea, Vincent P; Madanat, Rami; Muratoglu, Orhun; Malchau, Henrik
- Abstract
Background: Our main aim was to investigate whether obese patients were at increased risk of elevated metal ion levels and/or adverse local tissue reaction (ALTR) after being treated with articular surface replacement (ASR) hip arthroplasty. Methods: This study included 360 patients who underwent metal-on-metal (MoM) hip resurfacing (HRA) or total hip arthroplasty (THA). 95 patients (26%) were underweight/normal weight (BMI < 25 kg/m2), 139 (39%) were overweight (BMI 25–30 kg/m2), and 126 (36%) were obese (BMI ⩾ 30 kg/m2). Blood metal ion levels and patient-reported outcome measures (PROMs) were obtained, and a sub-cohort of 85 patients had MARS MRI performed. Logistic regression analyses were used to assess the associations between obesity and metal ions, as well as ALTR. Results: BMI was not associated with either elevated metal ion levels or ALTR. In HRA patients, female gender (OR 3.0; p = 0.019) and pain (OR 2.3; p = 0.046) were associated with elevated Co levels. Female patients had increased risk of elevated Cr levels (OR 3.0; p = 0.02). In THA patients, female gender (OR 2.2; p = 0.004) and VAS satisfaction (OR 2.1; p = 0.01) were associated with elevated Co levels. Female gender (OR 3.6; p = 0.001) and time from surgery (OR 1.4; p = 0.005) were associated with Cr levels. In the sub-cohort, ALTR was associated with Co levels (OR 16.1; p = 0.002) in HRA patients. Conclusion: Patients with BMI ⩾ 30 kg/m2 present no increased risk for elevated metal ion levels or development of ALTR.
- Subjects
SURGICAL complication risk factors; OBESITY complications; ARTIFICIAL joints; CHROMIUM; COBALT; LONGITUDINAL method; HEALTH outcome assessment; POSTOPERATIVE pain; RISK assessment; SEX distribution; TOTAL knee replacement; LOGISTIC regression analysis; BODY mass index; VISUAL analog scale; TREATMENT effectiveness; ODDS ratio
- Publication
Hip International, 2020, Vol 30, Issue 1, p78
- ISSN
1120-7000
- Publication type
Article
- DOI
10.1177/1120700019828705