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- Title
Recurrent Bacterial Meningitis Associated with C8 and IgA Deficiency.
- Authors
Veeder, Michael H.; Folds, James D.; Yount, William J.; Lee, Terrence J.
- Abstract
A patient with recurrent bacterialmeningitis wholackedcirculating C8, serum IgA, and secretory IgAis reported. The combinedabsence of C8and IgAdeficiency has not been previously noted. Although the association of disseminated neisserial infectionand absence of the terminalcomplement components is now well established, the deficiency of bactericidal capability as well as mucosal humoral defense may have been additive in predisposing the patient to recurrent meningitis. The pedigree was uninformative regarding possible linkage of these two uncommon genetic errors.
- Publication
Journal of Infectious Diseases, 1981, Vol 144, Issue 5, p399
- ISSN
0022-1899
- Publication type
Article