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- Title
Epidemiology of childhood IDDM in U.S. Virgin Islands from 1979 to 1988. Evidence of an epidemic in early 1980s and variation by degree of racial admixture.
- Authors
Tull, Eugene S.; Roseman, Jeffrey M.; Christian, Cora L. E.; Tull, E S; Roseman, J M; Christian, C L
- Abstract
<bold>Objective: </bold>The epidemiology of insulin-dependent diabetes mellitus (IDDM) was evaluated in a predominantly black population in the U.S. Virgin Islands.<bold>Research Design and Methods: </bold>Primary ascertainment of diabetic subjects was by retrospective review of hospital and clinic records, and IDDM was defined by Diabetes Epidemiology Research International Group criteria.<bold>Results: </bold>For the period 1979-1988, 28 children less than 15 yr of age were diagnosed with IDDM resulting in an average annual IDDM incidence rate (IR) of 7.5/100,000 (95% confidence interval 4.7-10.3). A significant increase in IDDM incidence (P less than 0.01) was observed when the IR rose to 28.4/100,000 in 1984. White children had the highest IR (28.9/100,000). The IR for Hispanics (7.2/100,000) was slightly higher than that for blacks (5.9/100,000). Among black children, a slight but nonsignificant male excess in incidence was observed (male-female ratio 1.5). When black or Hispanic patients were compared with age-matched control subjects with respect to grandparental race, the diabetic subjects had a greater percentage of white ancestry (P less than 0.02 and P less than 0.05, respectively). The incidence of IDDM in Caribbean blacks (West Indians) in the U.S. Virgin Islands was similar to blacks in the U.S.<bold>Conclusions: </bold>The epidemic of IDDM in 1984 provides support for a possible pandemic in the early 1980s.
- Publication
Diabetes Care, 1991, Vol 14, Issue 7, p558
- ISSN
0149-5992
- Publication type
journal article
- DOI
10.2337/diacare.14.7.558