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- Title
Magnetization transfer and frequency distribution effects in the SSFP ellipse.
- Authors
Wood, Tobias C.; Teixeira, Rui P. A. G.; Malik, Shaihan J.
- Abstract
Purpose: To demonstrate that quantitative magnetization transfer (qMT) parameters can be extracted from steady‐state free‐precession (SSFP) data with no external T1 map or banding artifacts. Methods: SSFP images with multiple MT weightings were acquired and qMT parameters fitted with a two‐stage elliptical signal model. Results: Monte Carlo simulations and data from a 3T scanner indicated that most qMT parameters could be recovered with reasonable accuracy. Systematic deviations from theory were observed in white matter, consistent with previous literature on frequency distribution effects. Conclusions: qMT parameters can be extracted from SSFP data alone, in a manner robust to banding artifacts, despite several confounds.
- Subjects
MONTE Carlo method; MAGNETIZATION transfer; DISTRIBUTION (Probability theory)
- Publication
Magnetic Resonance in Medicine, 2020, Vol 84, Issue 2, p857
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.28149