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- Title
Cancer: An acidic link.
- Authors
Devkota, Suzanne; Turnbaugh, Peter. J.
- Abstract
The article focuses on obesity and associated risk of cancer. It informs that obese people are at high risks of multiple cancers because obesity enhances the production of pro-inflammatory, and carcinogenic, bile acids by gut microorganisms. Researchers found out that deoxycholic acid, an obesity-associated by-product of microbial bile-acid metabolism contributes to hepatic inflammation and subsequent progression to cancer in obese mice.
- Subjects
OBESITY complications; CANCER; INFLAMMATION; BILE acids; MOUSE diseases
- Publication
Nature, 2013, Vol 499, Issue 7456, p37
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/nature12404