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- Title
Heavy ion carcinogenesis and human space exploration.
- Authors
Durante, Marco; Cucinotta, Francis A.
- Abstract
Before the human exploration of Mars or long-duration missions on the Earth's moon, the risk of cancer and other diseases from space radiation must be accurately estimated and mitigated. Space radiation, comprised of energetic protons and heavy nuclei, has been shown to produce distinct biological damage compared with radiation on Earth, leading to large uncertainties in the projection of cancer and other health risks, and obscuring evaluation of the effectiveness of possible countermeasures. Here, we describe how research in cancer radiobiology can support human missions to Mars and other planets.
- Subjects
CANCER research; HEAVY ions; RADIATION sources; ASTROPHYSICAL radiation; DISEASE risk factors; RADIOBIOLOGY; MARS (Planet); CHROMOSOME abnormalities; COMPARATIVE studies; DISEASE susceptibility; DNA; HEALTH; RESEARCH methodology; MEDICAL cooperation; PARTICLES (Nuclear physics); RADIATION; RADIATION carcinogenesis; RADIATION-protective agents; RESEARCH; SPACE flight; OCCUPATIONAL hazards; ENVIRONMENTAL exposure; EVALUATION research; RESEARCH personnel; PHARMACODYNAMICS
- Publication
Nature Reviews Cancer, 2008, Vol 8, Issue 6, p465
- ISSN
1474-175X
- Publication type
research
- DOI
10.1038/nrc2391