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- Title
Uterine carcinosarcoma - case report.
- Authors
Drăgușin, Roxana-Cristina; Dinu, Marina; Hodorog, Andreea-Denisa; Cismaru-Stăncioi, Andreea-Florentina; Tudorache, Ștefania; Aron, Raluca-Maria
- Abstract
Uterine carcinosarcoma (UCS) represents an extremely rare and aggressive gynecological neoplasm. This type of malignancy includes both carcinomatous and sarcomatous elements, and it carries a poor prognosis even when diagnosed at an early stage. The clinical features of UCS are similar to those of endometrial carcinoma. A 58-year-old menopausal female presented with severe pain and moderate vaginal bleeding for three weeks. The ultrasound examination described a thick endometrium (25 mm). The endometrial biopsy confirmed a moderate differentiated endometrioid carcinoma. The patient presented a remarkable rapid unfavorable evolution and underwent massive surgical resection. Postoperatively, immunohistochemistry of the specimen confirmed the uterine carcinosarcoma. Unfortunately, the patient was lost before starting any adjuvant therapy. The reported case presents a biphasic malignancy. It underlines the highly invasive nature of uterine carcinosarcoma and the extreme importance of the pathology findings.
- Subjects
ENDOMETRIAL cancer; UTERINE hemorrhage; CARCINOSARCOMAS; SURGICAL excision; ENDOMETRIUM; PATHOLOGY; PROGNOSIS
- Publication
Obstetrică şi Ginecologie, 2023, Vol 71, Issue 4, p174
- ISSN
1220-5532
- Publication type
Article