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- Title
Stem Cells: The planarian Prometheus, quantified.
- Authors
de Souza, Natalie
- Abstract
The article focuses on a study regarding the genetic regulators of a pluripotent adult stem cell system in planarians Schmidtea mediterranea. Peter Reddien and his colleagues at the Massachusetts Institute of Technology showed that a single neoblast can give rise, upon transplant, to the whole flatworm. Graduate student Dan Wagner found that sublethal doses of irradiation could yield a few surviving neoblasts through subsequent expansion of the cell yields in vivo clonal colonies.
- Subjects
GENETIC regulation; PLURIPOTENT stem cells; PLATYHELMINTHES; WAGNER, Dan; IRRADIATION; CLONE cells; MATHEMATICAL models
- Publication
Nature Methods, 2012, Vol 9, Issue 5, p432
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.2005