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- Title
Proteases, proteases and proteases for presentation.
- Authors
Herberts, Carla; Reits, Eric; Neefjes, Jacques
- Abstract
Reports that the tripeptidyl peptidase II (TPPII) acts as an alternative to the proteosomes in the major histocompatibility complex (MHC) class I antigen presentation pathway and generates an HIV Nef epitope recognized by specific cytotoxic T lymphocytes. Events of the MHC class I antigen presentation pathway; Role of TPPII in the class I antigen presentation pathway; Function of cytosolic peptidase.
- Subjects
MAJOR histocompatibility complex; PEPTIDASE; T cells
- Publication
Nature Immunology, 2003, Vol 4, Issue 4, p306
- ISSN
1529-2908
- Publication type
Article
- DOI
10.1038/ni0403-306