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- Title
Genetic polymorphism of interleukin-1β is associated with risk of type 1 diabetes mellitus in children.
- Authors
Krikovszky, Dóra; Vásárhelyi, Barna; Treszl, András; Körner, Anna; Tordai, Attila; Tulassay, Tivadar; Madácsy, László
- Abstract
Investigates the association of interleukin 1 (IL1)-beta C3954T polymorphism with the risk of pediatric type 1 diabetes mellitus (DM). Characteristics of type 1 DM; Role of a higher level of IL1-beta in the maintenance of auto-immune damage of pancreatic beta-cells; Higher prevalence of C3954T allele among children of type 1 DM.
- Subjects
INTERLEUKIN-1; GENETIC polymorphisms; DIABETES in children; DISEASE risk factors
- Publication
European Journal of Pediatrics, 2002, Vol 161, Issue 9, p507
- ISSN
0340-6199
- Publication type
Article
- DOI
10.1007/s00431-002-1030-9