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- Title
Effectiveness of Beta Blocker In Preventing Arrhythmia in Post Operative [CABG] Patients.
- Authors
Tarlekar, S. R.; Kane, G. R.; Jadhav, Uday; Tarlekar, A. S.
- Abstract
Introduction-Postoperative atrial fibrillation (POAF) is a potentially lethal and morbid complication after heart surgery. The present study was conducted to study the use of metoprolol in pre and post isolated CABG cases to reduce the incidence of atrial fibrillation. Material and methods- 50 cases and controls who had undergone isolated CABG surgery with extracorporeal circulation participated in a randomised research. The administration of metoprolol orally to the patients during the postoperative phase was randomised. The results included the identification of persistent arrhythmia that was symptomatic or needed medical attention. Patients having baseline left ventricular ejection fractions less than 35%, prior episodes of AF, a history of bronchospasm, second- and third-degree atrioventricular blocks, inadequate cardiac output, and heart failure were excluded from the trial. Results- In the metoprolol group, 10% patients experienced arrhythmias, compared to 23% in the control group (P=0.03). The arrhythmia that was seen the most commonly (85%) was AF. Arrhythmias occurred in 52% metoprolol-treated patients and 56% control patients among patients aged 70 or older with the 95% confidence interval for the risk was 0.10. Conclusion- In the postoperative period following CABG surgery, metoprolol is useful in reducing arrhythmia, and this effect was especially noticeable in the group of senior patients.
- Subjects
ARRHYTHMIA; VENTRICULAR ejection fraction; CORONARY artery bypass; ARTIFICIAL blood circulation; CARDIAC output; ATRIAL fibrillation; CARDIAC surgery
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2023, Vol 14, Issue 6, p2395
- ISSN
0975-3583
- Publication type
Article