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- Title
The metabolism of xylazine in rats.
- Authors
Park Choo, hea-Young; Choi, Sun-Ok
- Abstract
The biotransformation of xylazine, a widly used animal tranquilizer, was investigated in rats. After administration of xylazine, the existence of 2,6-dimethylphenylisothiocyanate, 2,6-dimenthyl-4-hydroxy-aniline and p-hydroxy-xylazine in urine was confirmed by the comparison with chemically prepared standards in GC/MS. The main metabolite, p-hydroxy xylazine was excreted as conjugated form.
- Publication
Archives of Pharmacal Research, 1991, Vol 14, Issue 4, p346
- ISSN
0253-6269
- Publication type
Article
- DOI
10.1007/BF02876882