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- Title
Introduction.
- Authors
Bauer, Christian; Kurtz, Armin
- Abstract
This article focuses on the effect of Oxygen supply on cellular and molecular metabolism. Oxygen is essentially involved in the metabolism of eukaryonts in which the reduction of oxygen to water is the main pathway for the cellular energy formation in the form of ATP. Insufficient oxygen supply of the organism therefore causes insufficient energy supply leading to restriction of cellular function and would ultimately cause cell death. Thus a drop of oxygen tension(hypoxia) induces the expression of genes, which enable the cells to adapt to oxygen deficiency and which contribute to improve the oxygen delivery to tissues.
- Subjects
OXYGEN; METABOLISM; PHYSIOLOGICAL transport of oxygen; CELLS; CELL death; HYPOXEMIA
- Publication
Kidney International, 1997, Vol 51, Issue 2, p371
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.1997.48