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- Title
Impact of Hemodialysis Duration on Coronary Artery Calcification Among Hemodialysis Patients Who Underwent Percutaneous Coronary Intervention.
- Authors
Iiya, Munehiro; Hikita, Hiroyuki; Yoshikawa, Hiroshi; Abe, Fumiyuki; Tsujihata, Shihoko; Ito, Naruhiko; Kanno, Yoshinori; Hishikari, Keiichi; Murai, Tadashi; Takahashi, Atsushi; Yonetsu, Taishi; Sasano, Tetsuo
- Abstract
Our study aimed to evaluate the prevalence and impact of coronary artery calcification (CAC) on hemodialysis (HD) patients with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). We enrolled 211 HD patients who underwent PCI (men: n = 155, age: 71 ± 1 0 years). Severe CAC was defined as calcification with an arc of 360° on intravascular ultrasound. Multivariate analysis was performed to determine the predictors of severe CAC. The impact of severe CAC on target lesion revascularization (TLR) was evaluated. Patients with severe CAC (46%) had a higher incidence of diabetes mellitus (DM) (79 vs 59%, P =.003) and longer HD duration (7.7 vs 3.4 years, P <.001) than those with non-severe CAC. Multivariate analysis demonstrated that DM, HD duration, and angiographic calcification were significant predictors for severe CAC (odds ratio 4.42, 1.13, and 6.62; P <.001, P <.001, and P <.001, respectively). After the median follow-up period of 580 days (interquartile range, 302–730 days), Kaplan–Meier curve analysis revealed that severe CAC was associated with an increased risk for TLR (χ2 12.7; P =.002). In HD patients with CAD after PCI, DM and HD duration were significant predictors for severe CAC. Furthermore, severe CAC was associated with an increased risk for TLR.
- Subjects
TRANSLUMINAL angioplasty; REVASCULARIZATION (Surgery); MULTIVARIATE analysis; TREATMENT duration; DIABETES; RISK assessment; MYOCARDIAL revascularization; KAPLAN-Meier estimator; CHI-squared test; HEMODIALYSIS; CORONARY artery calcification; ODDS ratio
- Publication
Angiology, 2022, Vol 73, Issue 8, p764
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/00033197211073407