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- Title
Postprandial Triglyceride, Glucose and Insulin Levels 10 Years After Bariatric Surgery in Women With Severe Obesity -- A Pilot Study: Part 1 -- Laparoscopic Greater Curvature Plication.
- Authors
METELCOVÁ, Tereza; HAINER, Vojtěch; HILL, Martin; KALOUSKOVÁ, Pavla; VRBÍKOVÁ, Jana; ŠRÁMKOVÁ, Petra; FRIED, Martin; BRAUNEROVÁ, Radka TAXOVÁ; KUNEŠOVÁ, Marie
- Abstract
The long-term effects of bariatric surgery on postprandial profiles in patients with obesity and type 2 diabetes (T2D) have not yet been investigated. Therefore, this study examined postprandial profiles before laparoscopic greater curvature plication (LGCP), and then at 2 and 10 years after surgery. The studied cohort included 10 women (mean age= 54.4±5 years) with obesity (mean BMI= 42.5±7.8 kg/m²) and T2D who underwent LGCP. All subjects underwent a standardized liquid mixed-meal test. For statistical evaluation, ANOVA with Bonferroni multiple comparison was used. Mean postprandial levels were significantly decreased 2 years after surgery. Responses 10 years after the surgery also remained significantly lower than before surgery. Changes observed during the follow-up were significant: glucose: F=34.5, p<0.001; insulin: F=49.3, p<0.001; triglycerides F=9.2, p<0.001. The long-term favorable effects of bariatric surgery on cardiometabolic health may be partly mediated by reductions in postprandial glucose, insulin, and triglyceride levels.
- Subjects
TRIGLYCERIDES; BARIATRIC surgery; OBESITY; LAPAROSCOPIC surgery; BODY mass index
- Publication
Physiological Research, 2023, Vol 72, pS399
- ISSN
0862-8408
- Publication type
Article
- DOI
10.33549/physiolres.935145