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- Title
CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information.
- Authors
Bartoli, Lisa; Fariselli, Piero; Krogh, Anders; Casadio, Rita
- Abstract
Motivation:The widespread coiled-coil structural motif in proteins is known to mediate a variety of biological interactions. Recognizing a coiled-coil containing sequence and locating its coiled-coil domains are key steps towards the determination of the protein structure and function. Different tools are available for predicting coiled-coil domains in protein sequences, including those based on position-specific score matrices and machine learning methods.
- Subjects
STRUCTURAL bioinformatics; PROTEIN analysis; AMINO acid sequence; MARKOV processes; MACHINE learning
- Publication
Bioinformatics, 2009, Vol 25, Issue 21, p2757
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btp539