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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas.
Published in:
2008
By:
- Pfister, Stefan;
- Janzarik, Wibke G.;
- Remke, Marc;
- Ernst, Aurélie;
- Werft, Wiebke;
- Becker, Natalia;
- Toedt, Grischa;
- Wittmann, Andrea;
- Kratz, Christian;
- Olbrich, Heike;
- Ahmadi, Rezvan;
- Thieme, Barbara;
- Joos, Stefan;
- Radlwimmer, Bernhard;
- Kulozik, Andreas;
- Pietsch, Torsten;
- Herold-Mende, Christel;
- Gnekow, Astrid;
- Reifenberger, Guido;
- Korshunov, Andrey
Publication type:
journal article
ELM—the database of eukaryotic linear motifs.
Published in:
Nucleic Acids Research, 2012, p. D242, doi. 10.1093/nar/gkr1064
By:
- Dinkel, Holger;
- Michael, Sushama;
- Weatheritt, Robert J.;
- Davey, Norman E.;
- Van Roey, Kim;
- Altenberg, Brigitte;
- Toedt, Grischa;
- Uyar, Bora;
- Seiler, Markus;
- Budd, Aidan;
- Jödicke, Lisa;
- Dammert, Marcel A.;
- Schroeter, Christian;
- Hammer, Maria;
- Schmidt, Tobias;
- Jehl, Peter;
- McGuigan, Caroline;
- Dymecka, Magdalena;
- Chica, Claudia;
- Luck, Katja
Publication type:
Article
Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data.
Published in:
BMC Bioinformatics, 2011, v. 12, n. 1, p. 138, doi. 10.1186/1471-2105-12-138
By:
- Becker, Natalia;
- Toedt, Grischa;
- Lichter, Peter;
- Benner, Axel
Publication type:
Article
FACT -- a framework for the functional interpretation of high-throughput experiments.
Published in:
BMC Bioinformatics, 2005, v. 6, p. 1, doi. 10.1186/1471-2105-6-161
By:
- Kokocinski, Felix;
- Delhomme, Nicolas;
- Wrobel, Gunnar;
- Hummerich, Lars;
- Toedt, Grischa;
- Lichter, Peter
Publication type:
Article
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.
Published in:
Nature Cell Biology, 2015, v. 17, n. 8, p. 1074, doi. 10.1038/ncb3201
By:
- Wheway, Gabrielle;
- Schmidts, Miriam;
- Mans, Dorus A.;
- Szymanska, Katarzyna;
- Nguyen, Thanh-Minh T.;
- Racher, Hilary;
- Phelps, Ian G.;
- Toedt, Grischa;
- Kennedy, Julie;
- Wunderlich, Kirsten A.;
- Sorusch, Nasrin;
- Abdelhamed, Zakia A.;
- Natarajan, Subaashini;
- Herridge, Warren;
- van Reeuwijk, Jeroen;
- Horn, Nicola;
- Boldt, Karsten;
- Parry, David A.;
- Letteboer, Stef J. F.;
- Roosing, Susanne
Publication type:
Article
Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation.
Published in:
Neuro-Oncology, 2012, v. 14, n. 1, p. 64, doi. 10.1093/neuonc/nor182
By:
- Kees, Tim;
- Lohr, Jennifer;
- Noack, Johannes;
- Mora, Rodrigo;
- Gdynia, Georg;
- Tödt, Grischa;
- Ernst, Aurélie;
- Radlwimmer, Bernhard;
- Falk, Christine S.;
- Herold-Mende, Christel;
- Régnier-Vigouroux, Anne
Publication type:
Article
Effective transcriptome amplification for expression profiling on sense-oriented oligonucleotide microarrays.
Published in:
Nucleic Acids Research, 2005, v. 33, n. 3, p. e29, doi. 10.1093/nar/gni029
By:
- Schlingemann, Joerg;
- Thuerigen, Olaf;
- Ittrich, Carina;
- Toedt, Grischa;
- Kramer, Heidi;
- Hahn, Meinhard;
- Lichter, Peter
Publication type:
Article
Site‐specific protein modification to identify the MutL interface of MutH.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 3, p. 819, doi. 10.1093/nar/gkg191
By:
- Toedt, Grischa H.;
- Krishnan, Ravi;
- Friedhoff, Peter
Publication type:
Article
Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling.
Published in:
International Journal of Cancer, 2006, v. 119, n. 4, p. 792, doi. 10.1002/ijc.21901
By:
- Tews, Bjoern;
- Felsberg, Joerg;
- Hartmann, Christian;
- Kunitz, Annegret;
- Hahn, Meinhard;
- Toedt, Grischa;
- Neben, Kai;
- Hummerich, Lars;
- von Deimling, Andreas;
- Reifenberger, Guido;
- Lichter, Peter
Publication type:
Article
Molecular signatures classify astrocytic gliomas by IDH1 mutation status.
Published in:
International Journal of Cancer, 2011, v. 128, n. 5, p. 1095, doi. 10.1002/ijc.25448
By:
- Toedt, Grischa;
- Barbus, Sebastian;
- Wolter, Marietta;
- Felsberg, Jörg;
- Tews, Björn;
- Blond, Frederic;
- Sabel, Michael C.;
- Hofmann, Stefanie;
- Becker, Natalia;
- Hartmann, Christian;
- Ohgaki, Hiroko;
- von Deimling, Andreas;
- Wiestler, Otmar D.;
- Hahn, Meinhard;
- Lichter, Peter;
- Reifenberger, Guido;
- Radlwimmer, Bernhard
Publication type:
Article
Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma.
Published in:
Genes, Chromosomes & Cancer, 2013, v. 52, n. 3, p. 250, doi. 10.1002/gcc.22025
By:
- Wu, Hui;
- Haag, Daniel;
- Muley, Thomas;
- Warth, Arne;
- Zapatka, Marc;
- Toedt, Grischa;
- Pscherer, Armin;
- Hahn, Meinhard;
- Rieker, Ralf J.;
- Wachter, David L.;
- Meister, Michael;
- Schnabel, Philipp;
- Müller‐Decker, Karin;
- Rogers, Michael A.;
- Hoffmann, Hans;
- Lichter, Peter
Publication type:
Article
Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.
Published in:
Genes, Chromosomes & Cancer, 2010, v. 49, n. 1, p. 9, doi. 10.1002/gcc.20714
By:
- Freier, Kolja;
- Knoepfle, Karl;
- Flechtenmacher, Christa;
- Pungs, Susanne;
- Devens, Frauke;
- Toedt, Grischa;
- Hofele, Christof;
- Joos, Stefan;
- Lichter, Peter;
- Radlwimmer, Bernhard
Publication type:
Article
Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.
Published in:
Genes, Chromosomes & Cancer, 2007, v. 46, n. 9, p. 839, doi. 10.1002/gcc.20471
By:
- Pfister, Stefan;
- Remke, Marc;
- Toedt, Grischa;
- Werft, Wiebke;
- Benner, Axel;
- Mendrzyk, Frank;
- Wittmann, Andrea;
- Devens, Frauke;
- von Hoff, Katja;
- Rutkowski, Stefan;
- Kulozik, Andreas;
- Radlwimmer, Bernhard;
- Scheurlen, Wolfram;
- Lichter, Peter;
- Korshunov, Andrey
Publication type:
Article
Isochromosome breakpoints on 17p in medulloblastoma are flanked by different classes of DNA sequence repeats.
Published in:
Genes, Chromosomes & Cancer, 2006, v. 45, n. 4, p. 401, doi. 10.1002/gcc.20304
By:
- Frank Mendrzyk;
- Andrey Korshunov;
- Grischa Toedt;
- Frank Schwarz;
- Bernhard Korn;
- Stefan Joos;
- Andreas Hochhaus;
- Claudia Schoch;
- Peter Lichter;
- Bernhard Radlwimmer
Publication type:
Article
Recurrent coamplification of cytoskeleton‐associated genes EMS1 and SHANK2 with CCND1 in oral squamous cell carcinoma.
Published in:
Genes, Chromosomes & Cancer, 2006, v. 45, n. 2, p. 118, doi. 10.1002/gcc.20270
By:
- Kolja Freier;
- Carsten Sticht;
- Christof Hofele;
- Christa Flechtenmacher;
- Daniel Stange;
- Laura Puccio;
- Grischa Toedt;
- Bernhard Radlwimmer;
- Peter Lichter;
- Stefan Joos
Publication type:
Article
Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization.
Published in:
Genes, Chromosomes & Cancer, 2005, v. 43, n. 3, p. 294, doi. 10.1002/gcc.20186
By:
- Boris Zielinski;
- Sandrine Gratias;
- Grischa Toedt;
- Frank Mendrzyk;
- Daniel E. Stange;
- Bernhard Radlwimmer;
- Dietmar R. Lohmann;
- Peter Lichter
Publication type:
Article
NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish.
Published in:
PLoS Genetics, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pgen.1005574
By:
- Dona, Margo;
- Bachmann-Gagescu, Ruxandra;
- Texier, Yves;
- Toedt, Grischa;
- Hetterschijt, Lisette;
- Tonnaer, Edith L.;
- Peters, Theo A.;
- van Beersum, Sylvia E. C.;
- Bergboer, Judith G. M.;
- Horn, Nicola;
- de Vrieze, Erik;
- Slijkerman, Ralph W. N.;
- van Reeuwijk, Jeroen;
- Flik, Gert;
- Keunen, Jan E.;
- Ueffing, Marius;
- Gibson, Toby J.;
- Roepman, Ronald;
- Boldt, Karsten;
- Kremer, Hannie
Publication type:
Article
Nos2 Inactivation Promotes the Development of Medulloblastoma in Ptch1<sup>+/-</sup> Mice by Deregulation of Gap43-Dependent Granule Cell Precursor Migration.
Published in:
PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002572
By:
- Haag, Daniel;
- Zipper, Petra;
- Westrich, Viola;
- Karra, Daniela;
- Pfleger, Karin;
- Toedt, Grischa;
- Blond, Frederik;
- Delhomme, Nicolas;
- Hahn, Meinhard;
- Reifenberger, Julia;
- Reifenberger, Guido;
- Lichter, Peter
Publication type:
Article
penalizedSVM: a R-package for feature selection SVM classification.
Published in:
Bioinformatics, 2009, v. 25, n. 13, p. 1711, doi. 10.1093/bioinformatics/btp286
By:
- Natalia Becker;
- Wiebke Werft;
- Grischa Toedt;
- Peter Lichter;
- Axel Benner
Publication type:
Article
A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16747-y
By:
- Reich, Stefan;
- Nguyen, Chi D. L.;
- Has, Canan;
- Steltgens, Sascha;
- Soni, Himanshu;
- Coman, Cristina;
- Freyberg, Moritz;
- Bichler, Anna;
- Seifert, Nicole;
- Conrad, Dominik;
- Knobbe-Thomsen, Christiane B.;
- Tews, Björn;
- Toedt, Grischa;
- Ahrends, Robert;
- Medenbach, Jan
Publication type:
Article

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