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- Title
OCENA STĘŻENIA NEOPTERYNY U PACJENTÓW ZE ŚWIEŻYM UDAREM NIEDOKRWIENNYM.
- Authors
KORZENIOWSKA, KATARZYNA; WIETLICKA-KOKOSZANEK, IRMINA; KAźMIER-CZAK, MIROSŁAW; CHMARA, EWA; JABŁECKA, ANNA
- Abstract
Current results of studies confirm that one of the elements of the atherosclerotic process is inflammatory. One of the marker inflammatory is neopterin produced by macrophages under the influence INF-g. The aim of this study was to estimate the prognostic value of neopterin in patients after ischemic cerebral stroke -- does its increase influence on quality of life and course of disease. Serum neopterin assessment was conducted in 29 patients with recent ischemic stroke. Control group consisted of 20 healthy volunteers. Neopterin was assessed by radioimmunoassay (RIA) with MP Biomedicals Results: Statistically significant increase of neopterin concentration was observed in patients with recent ischemic cerebral stroke compared with control group (10,45±5,2 nmol/l vs. 2,97±0,9 nmol/l). It was not observed a correlation between disease stage and neopterin concentration. Conclusions: 1. In patients with recent ischemic cerebral stroke statistically significant increase of neopterin concentration was observed compared with control group. 2. Concentrations of neopterin do not influence on prognosis and course of diseases in patients with ischemic cerebral stroke.
- Subjects
NEOPTERIN; ISCHEMIA; ATHEROSCLEROSIS; INFLAMMATION; QUALITY of life; DISEASE risk factors; PATIENTS
- Publication
Problemy Terapii Monitorowanej, 2008, Vol 19, Issue 3, p203
- ISSN
0867-6348
- Publication type
Article