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- Title
Elevated serotonin and 5-HIAA in the brainstem and lower serotonin turnover in the prefrontal cortex of suicides.
- Authors
Bach, Helene; Huang, Yung‐Yu; Underwood, Mark D.; Dwork, Andrew J.; Mann, J. John; Arango, Victoria
- Abstract
Using high pressure liquid chromatography, we find more brainstem 5‐HT and 5‐HIAA in suicides compared with nonpsychiatric, sudden death controls throughout the rostrocaudal extent of the brainstem DRN and MRN. This suggests that 5‐HT synthesis in suicides is greater within all DRN subnuclei and the MRN compared with controls.
- Publication
Synapse, 2014, Vol 68, Issue 3, p127
- ISSN
0887-4476
- Publication type
Article
- DOI
10.1002/syn.21695