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- Title
Gleevec casts a pox on poxviruses.
- Authors
McFadden, Grant
- Abstract
Reports on the finding that the tyrosine kinase inhibitor Gleevec, currently used to treat cancers such as chronic myeloid leukemia, can also function as an antiviral drug to treat poxvirus infections. Ability of Gleevec to block the egress of poxviruses such as vaccinia virus from infected cells; Morphogenesis of poxviruses in the cytoplasm of infected cells.
- Subjects
TYROSINE; CANCER treatment; MYELOID leukemia; ANTIVIRAL agents; POXVIRUSES
- Publication
Nature Medicine, 2005, Vol 11, Issue 7, p711
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm0705-711