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Highlights.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 845, doi. 10.1002/cpt.2392
Publication type:
Article
Diversity in Clinical Pharmacology and Therapeutics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 837, doi. 10.1002/cpt.2391
Publication type:
Article
ASCPT News.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 847, doi. 10.1002/cpt.2390
Publication type:
Article
In This Issue.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 835, doi. 10.1002/cpt.2389
Publication type:
Article
Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) and Ductus Arteriosus Closure After Premature Birth.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1087, doi. 10.1002/cpt.2380
By:
- Bouazza, Naïm;
- Treluyer, Jean‐Marc;
- Foissac, Frantz;
- Urien, Saïk;
- Aikio, Outi;
- Roze, Jean‐Christophe;
- Hallman, Mikko
Publication type:
Article
Mapping the miRNA‐mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1106, doi. 10.1002/cpt.2379
By:
- Powell, Nicholas R.;
- Zhao, Harrison;
- Ipe, Joseph;
- Liu, Yunlong;
- Skaar, Todd C.
Publication type:
Article
FDA Breakthrough Therapy Designation–Trial Design and More – Commentary.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 869, doi. 10.1002/cpt.2378
By:
- Corrigan‐Curay, Jacqueline;
- Stein, Peter
Publication type:
Article
Factors Influencing Plasma Coproporphyrin‐I Concentration as Biomarker of OATP1B Activity in Patients With Rheumatoid Arthritis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1096, doi. 10.1002/cpt.2375
By:
- Ono, Hiroyuki;
- Tanaka, Ryota;
- Suzuki, Yosuke;
- Oda, Ayako;
- Ozaki, Takashi;
- Tatsuta, Ryosuke;
- Maeshima, Keisuke;
- Ishii, Koji;
- Ohno, Keiko;
- Shibata, Hirotaka;
- Itoh, Hiroki
Publication type:
Article
Association of Parenteral Anticoagulation Therapy With Outcomes in Non–ST‐Segment Elevation Acute Coronary Syndrome Patients Without Invasive Therapy: Findings from the Improving Care for Cardiovascular Disease in China (CCC) project.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1119, doi. 10.1002/cpt.2370
By:
- Liu, Yuan‐Hui;
- Fan, Hua‐Lin;
- Zeng, Li‐Huan;
- Duan, Chong‐Yang;
- Chen, Guo;
- Chen, Peng‐Yuan;
- Zhao, Dong;
- Liu, Jing;
- Hao, Yong‐Chen;
- He, Wen‐Fei;
- Tao, Sha;
- Wei, Xue‐Biao;
- Jiang, Lei;
- Guo, Wei;
- Guo, Yan‐Song;
- Chen, Wei;
- Li, Jun;
- Hu, Yun‐Zhao;
- Li, Wen‐Sheng;
- Chen, Yi‐Yue
Publication type:
Article
Methadone Destabilizes Cardiac Repolarization During Sleep.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1066, doi. 10.1002/cpt.2368
By:
- Solhjoo, Soroosh;
- Punjabi, Naresh M.;
- Ivanescu, Andrada E.;
- Crainiceanu, Ciprian;
- Gaynanova, Irina;
- Wicken, Cassie;
- Buckenmaier, Chester;
- Haigney, Mark C.
Publication type:
Article
Scholarly Productivity in Clinical Pharmacology Amid Pandemic‐Related Workforce Disruptions: Are Men and Women Affected Equally?
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 841, doi. 10.1002/cpt.2358
By:
- Gerding, Alethea B.;
- Swan, Sharon J.;
- Brayer, Kimberly A.;
- Abdel‐Rahman, Susan M.
Publication type:
Article
Cost to Medicare of Delayed Adalimumab Biosimilar Availability.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1050, doi. 10.1002/cpt.2322
By:
- Lee, ChangWon C.;
- Najafzadeh, Mehdi;
- Kesselheim, Aaron S.;
- Sarpatwari, Ameet
Publication type:
Article
Assessing the Impact of US Food and Drug Administration Breakthrough Therapy Designation Timing on Trial Characteristics and Development Speed.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1018, doi. 10.1002/cpt.2318
By:
- Pregelj, Lisette;
- Hine, Damian C.;
- Kesselheim, Aaron S.;
- Darrow, Jonathan J.
Publication type:
Article
A Study of Regulatory Challenges of Pediatric Oncology Phase I/II Trial Submissions and Guidance on Protocol Development.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1025, doi. 10.1002/cpt.2319
By:
- Beck, Lydia;
- Witt, Ruth;
- Nesper‐Brock, Martina;
- Milde, Till;
- Hettmer, Simone;
- Frühwald, Michael C.;
- Rössig, Claudia;
- Fischer, Matthias;
- Reinhardt, Dirk;
- Taylor, Lenka A.;
- Riedel, Claudia;
- Witt, Olaf;
- van Tilburg, Cornelis M.
Publication type:
Article
Coprescription of Opioids With Other Medications and Risk of Opioid Overdose.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1011, doi. 10.1002/cpt.2314
By:
- Khan, Nazleen F.;
- Bykov, Katsiaryna;
- Glynn, Robert J.;
- Barnett, Michael L.;
- Gagne, Joshua J.
Publication type:
Article
Inclusion of Infants and Neonates in Pediatric Orphan Product Approvals.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 997, doi. 10.1002/cpt.2306
By:
- Park, Kyunghun;
- Virparia, Riddhi;
- Green, Dionna J.;
- Epps, Carla;
- Wharton, Gerold T.;
- McCune, Susan K.;
- Burckart, Gilbert J.
Publication type:
Article
Translational Pharmacogenomics: Discovery, Evidence Synthesis and Delivery of Race‐Conscious Medicine.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 909, doi. 10.1002/cpt.2357
By:
- Davis, Brittney H.;
- Limdi, Nita A.
Publication type:
Article
Medication Errors During Treatment with New Oral Anticancer Agents: Consequences for Clinical Practice Based on the AMBORA Study.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1075, doi. 10.1002/cpt.2338
By:
- Schlichtig, Katja;
- Dürr, Pauline;
- Dörje, Frank;
- Fromm, Martin F.
Publication type:
Article
Benefit‐Risk Assessment of Off‐Label Drug Use in Children: The Bravo Framework.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 952, doi. 10.1002/cpt.2336
By:
- van der Zanden, Tjitske M.;
- Mooij, Miriam G.;
- Vet, Nienke J.;
- Neubert, Antje;
- Rascher, Wolfgang;
- Lagler, Florian B.;
- Male, Christoph;
- Grytli, Helene;
- Halvorsen, Thomas;
- de Hoog, Matthijs;
- de Wildt, Saskia N.
Publication type:
Article
Assessment of Drugs Approved by Public Knowledge‐Based Applications (Kouchi‐shinsei) During the Last Two Decades in Japan.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1127, doi. 10.1002/cpt.2332
By:
- Maeda, Hideki;
- Fukuda, Yuka;
- Uchida, Marika
Publication type:
Article
Improving Knowledge on Safety is Key to Enabling Drug Access for Pregnant and Breastfeeding Women.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 866, doi. 10.1002/cpt.2325
By:
- Chappell, Lucy C.;
- Tong, Stephen
Publication type:
Article
A Semimechanistic Pharmacokinetic Model for Depot Medroxyprogesterone Acetate and Drug–Drug Interactions With Antiretroviral and Antituberculosis Treatment.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1057, doi. 10.1002/cpt.2324
By:
- Francis, Jose;
- Mngqibisa, Rosie;
- McIlleron, Helen;
- Kendall, Michelle A;
- Wu, Xingye;
- Dooley, Kelly E.;
- Firnhaber, Cynthia;
- Godfrey, Catherine;
- Cohn, Susan E.;
- Denti, Paolo
Publication type:
Article
Interaction Between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early‐Stage Breast Cancer.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1038, doi. 10.1002/cpt.2311
By:
- Cairns, Junmei;
- Kalari, Krishna R.;
- Ingle, James N.;
- Shepherd, Lois E.;
- Ellis, Matthew J.;
- Goss, Paul E.;
- Barman, Poulami;
- Carlson, Erin E.;
- Goodnature, Barbara;
- Goetz, Matthew P.;
- Weinshilboum, Richard M.;
- Gao, Huanyao;
- Wang, Liewei
Publication type:
Article
Clinical Pharmacology Worldwide: A Global Health Perspective.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 946, doi. 10.1002/cpt.2274
By:
- Wenning, Larissa;
- Pillai, Goonaseelan;
- Knepper, Todd C.;
- Ilic, Katarina;
- Ali, Ali Mohamed;
- Hibma, Jennifer E.
Publication type:
Article
Commentary on "Sex and Gender Differences in Clinical Pharmacology: Implications for Transgender Medicine".
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 863, doi. 10.1002/cpt.2305
Publication type:
Article
Malaria PK/PD and the Role Pharmacometrics Can Play in the Global Health Arena: Malaria Treatment Regimens for Vulnerable Populations.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 926, doi. 10.1002/cpt.2238
By:
- Hughes, Emma;
- Wallender, Erika;
- Mohamed Ali, Ali;
- Jagannathan, Prasanna;
- Savic, Radojka M.
Publication type:
Article
Sex and Gender Differences in Clinical Pharmacology: Implications for Transgender Medicine.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 897, doi. 10.1002/cpt.2234
By:
- Cirrincione, Lauren R.;
- Huang, Kai J.
Publication type:
Article
Trends in Postpartum Opioid Prescribing: A Time Series Analysis.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1004, doi. 10.1002/cpt.2307
By:
- Zipursky, Jonathan S.;
- Pang, Andrea;
- Paterson, J. Michael;
- Austin, Peter C.;
- Mamdani, Muhammad;
- Gomes, Tara;
- Ray, Joel G.;
- Juurlink, David N.
Publication type:
Article
Exposure‐Response Relationships in Patients With HER2‐Positive Metastatic Breast Cancer and Other Solid Tumors Treated With Trastuzumab Deruxtecan.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 986, doi. 10.1002/cpt.2291
By:
- Yin, Ophelia;
- Iwata, Hiroji;
- Lin, Chia‐Chi;
- Tamura, Kenji;
- Watanabe, Junichiro;
- Wada, Russ;
- Kastrissios, Helen;
- AbuTarif, Malaz;
- Garimella, Tushar;
- Lee, Caleb;
- Zhang, Lin;
- Shahidi, Javad;
- LaCreta, Frank
Publication type:
Article
The Case for Expanding the FDA Box Warning on Clopidogrel to CYP2C19 Intermediate Metabolizers.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 860, doi. 10.1002/cpt.2215
By:
- Liu, Michelle;
- Roden, Dan M.;
- Peterson, Josh F.
Publication type:
Article
Impact of Multiple Prescriptions With Anticholinergic Properties on Adverse Clinical Outcomes in the Elderly: A Longitudinal Cohort Study in Taiwan.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 966, doi. 10.1002/cpt.2217
By:
- Hsu, Wen‐Han;
- Huang, Shih‐Tsung;
- Lu, Wan‐Hsuan;
- Wen, Yu‐Wen;
- Chen, Liang‐Kung;
- Hsiao, Fei‐Yuan
Publication type:
Article
A Personalized Medicine Approach to Guide Allopurinol Use and Prevent Serious Adverse Events: Ethnicity Is Not a Proxy for Genetics.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 852, doi. 10.1002/cpt.2124
Publication type:
Article
Assuring Access to Safe Medicines in Pregnancy and Breastfeeding.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 941, doi. 10.1002/cpt.2212
By:
- Nooney, Janet;
- Thor, Shannon;
- de Vries, Corinne;
- Clements, John;
- Sahin, Leyla;
- Hua, Wei;
- Everett, Darcie;
- Zaccaria, Cosimo;
- Ball, Robert;
- Saint‐Raymond, Agnes;
- Yao, Lynne;
- Raine, June;
- Kweder, Sandra
Publication type:
Article
Use of Partial Area Under the Curve in Bioavailability or Bioequivalence Assessments: A Regulatory Perspective.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 880, doi. 10.1002/cpt.2174
By:
- Fang, Lanyan;
- Uppoor, Ramana;
- Xu, Mingjiang;
- Sharan, Satish;
- Zhu, Hao;
- Tampal, Nilufer;
- Li, Bing;
- Zhang, Lei;
- Lionberger, Robert;
- Zhao, Liang
Publication type:
Article
Optimizing Pediatric Medicine Developments in the European Union Through Pragmatic Approaches.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 871, doi. 10.1002/cpt.2152
By:
- Rei Bolislis, Winona;
- Bejeuhr, Gesine;
- Benzaghou, Fawzi;
- Corriol‐Rohou, Solange;
- Herrero‐Martinez, Esteban;
- Hildebrand, Heidrun;
- Hill‐Venning, Claire;
- Hoogland, Hans;
- Johnson, Craig;
- Joos, Angelika;
- Vart, Richard;
- Le Visage, Geneviève;
- Kühler, Thomas C.
Publication type:
Article
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 888, doi. 10.1002/cpt.2149
By:
- Crews, Kristine R.;
- Monte, Andrew A.;
- Huddart, Rachel;
- Caudle, Kelly E.;
- Kharasch, Evan D.;
- Gaedigk, Andrea;
- Dunnenberger, Henry M.;
- Leeder, J. Steven;
- Callaghan, John T.;
- Samer, Caroline Flora;
- Klein, Teri E.;
- Haidar, Cyrine E.;
- Van Driest, Sara L.;
- Ruano, Gualberto;
- Sangkuhl, Katrin;
- Cavallari, Larisa H.;
- Müller, Daniel J.;
- Prows, Cynthia A.;
- Nagy, Mohamed;
- Somogyi, Andrew A.
Publication type:
Article
Transferability of Ancestry‐Specific and Cross‐Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 975, doi. 10.1002/cpt.2135
By:
- El‐Boraie, Ahmed;
- Chenoweth, Meghan J.;
- Pouget, Jennie G.;
- Benowitz, Neal L.;
- Fukunaga, Koya;
- Mushiroda, Taisei;
- Kubo, Michiaki;
- Nollen, Nicole L.;
- Sanderson Cox, Lisa;
- Lerman, Caryn;
- Knight, Jo;
- Tyndale, Rachel F.
Publication type:
Article
Drug‐Drug Interactions Involving Renal OCT2/MATE Transporters: Clinical Risk Assessment May Require Endogenous Biomarker‐Informed Approach.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 855, doi. 10.1002/cpt.2089
By:
- Mathialagan, Sumathy;
- Feng, Bo;
- Rodrigues, A. David;
- Varma, Manthena V. S.
Publication type:
Article
Issue Information.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 827, doi. 10.1002/cpt.1904
Publication type:
Article

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