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- Title
Intraocular myofibroblastoma in an infant: a case report.
- Authors
Ning Hua; Jinyong Lin; Xuehan Qian; Nan Wei; Shaozhen Zhao
- Abstract
Background: Myofibroblastoma is a benign tumor composed of spindle cells and bands of hyalinized collagen. Intraocular myofibroblastoma in infancy is rarely encountered. Case presentation: The present study reports the case of a 4-month-old female baby with intraocular myofibroblastoma. She was suspected as corneal perforation due to the rupture of a corneal neoplasm in the right eye. The anterior segment was also involved according to the Color Doppler ultrasonography. A surgical exploration was performed and the protuberant part of the mass was resected. Conventional HE staining showed numerous spindle-shaped cells with bands of collagen beneath multilayers of well-differentiated corneal epithelia. Immunohistochemical staining demonstrated the tumor cells were strong positive for vimentin and smooth muscle actin, while negative for S-100 protein. The mass was confirmed as myofibroblastoma. After 12 month follow-up, there was no apparent growth of the tumor. Conclusions: Myofibroblastoma is a very rare type of intraocular neoplasm, which may have complicated manifestation and could be misdiagnosed as dermoid or Peter’s anomaly. Histopathological and immunohistochemical staining is crucial to form a precise diagnosis.
- Publication
BMC Ophthalmology, 2015, Vol 15, Issue 1, p113
- ISSN
1471-2415
- Publication type
Article
- DOI
10.1186/s12886-015-0082-3