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Rare Nivolumab-associated Super Hyper Progressive Disease in Patients With Advanced Gastric Cancer.
Published in:
In Vivo, 2021, v. 35, n. 3, p. 1865, doi. 10.21873/invivo.12449
By:
- YUTARO KUBOTA;
- KIYOSHI YOSHIMURA;
- KAZUYUKI HAMADA;
- YUYA HIRASAWA;
- MIDORI SHIDA;
- MAKOTO TANIGUCHI;
- HIROTO MATSUI;
- HIROTSUGU ARIIZUMI;
- TOMOYUKI ISHIGURO;
- NORIHIRO SUZUKI;
- RYOTARO OHKUMA;
- TAKEHIKO SAMBE;
- HIROO ISHIDA;
- ATSUSHI HORIIKE;
- SATOSHI WADA;
- JUNJI TSURUTANI;
- SANJU IWAMOTO;
- NAOKI UCHIDA;
- YUJI KIUCHI;
- SHINICHI KOBAYASHI
Publication type:
Article
Case Report: Combined pembrolizumab, 5-fluorouracil, and cisplatin therapy were remarkably effective in p16- positive squamous cell carcinoma of unknown primary.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1231986
By:
- Risako Suzuki;
- Kazuyuki Hamada;
- Ryotaro Ohkuma;
- Mayumi Homma;
- Toshiaki Tsurui;
- Nana Iriguchi;
- Tomoyuki Ishiguro;
- Yuya Hirasawa;
- Hirotsugu Ariizumi;
- Yutaro Kubota;
- Atsushi Horiike;
- Kiyoshi Yoshimura;
- Satoshi Wada;
- Toshiko Yamochi;
- Takuya Tsunoda
Publication type:
Article
Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer.
Published in:
Cancer Immunology, Immunotherapy, 2024, v. 73, n. 2, p. 1, doi. 10.1007/s00262-023-03608-y
By:
- Otsuka, Koji;
- Isobe, Junya;
- Asai, Yoshiyuki;
- Nakano, Tomohisa;
- Hattori, Kouya;
- Ariyoshi, Tomotake;
- Yamashita, Takeshi;
- Motegi, Kentaro;
- Saito, Akira;
- Kohmoto, Masahiro;
- Hosonuma, Masahiro;
- Kuramasu, Atsuo;
- Baba, Yuta;
- Murayama, Masakazu;
- Narikawa, Yoichiro;
- Toyoda, Hitoshi;
- Funayama, Eiji;
- Tajima, Kohei;
- Shida, Midori;
- Hirasawa, Yuya
Publication type:
Article
A high number of PD-L1+ CD14+ monocytes in peripheral blood is correlated with shorter survival in patients receiving immune checkpoint inhibitors.
Published in:
Cancer Immunology, Immunotherapy, 2021, v. 70, n. 2, p. 337, doi. 10.1007/s00262-020-02686-6
By:
- Ando, Kiyohiro;
- Hamada, Kazuyuki;
- Shida, Midori;
- Ohkuma, Ryotaro;
- Kubota, Yutaro;
- Horiike, Atsushi;
- Matsui, Hiroto;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Watanabe, Makoto;
- Onoue, Rie;
- Tsurutani, Junji;
- Yoshimura, Kiyoshi;
- Tsunoda, Takuya;
- Kobayashi, Shinichi;
- Wada, Satoshi
Publication type:
Article
Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-59677-1
By:
- Murayama, Masakazu;
- Hosonuma, Masahiro;
- Kuramasu, Atsuo;
- Kobayashi, Sei;
- Sasaki, Akiko;
- Baba, Yuta;
- Narikawa, Yoichiro;
- Toyoda, Hitoshi;
- Isobe, Junya;
- Funayama, Eiji;
- Tajima, Kohei;
- Sasaki, Aya;
- Maruyama, Yuki;
- Yamazaki, Yoshitaka;
- Shida, Midori;
- Hamada, Kazuyuki;
- Hirasawa, Yuya;
- Tsurui, Toshiaki;
- Ariizumi, Hirotsugu;
- Ishiguro, Tomoyuki
Publication type:
Article
Novel quantitative immunohistochemical analysis for evaluating PD-L1 expression with phosphor-integrated dots for predicting the efficacy of patients with cancer treated with immune checkpoint inhibitors.
Published in:
Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1260492
By:
- Ryotaro Ohkuma;
- Sakiko Miura;
- Satoshi Muto;
- Yoshitaka Toyomasu;
- Yuki Fujimoto;
- Katsuaki Ieguchi;
- Nobuyuki Onishi;
- Takashi Shimizu;
- Makoto Watanabe;
- Daisuke Takayanagi;
- Tsubasa Goshima;
- Atsushi Horiike;
- Kazuyuki Hamada;
- Hirotsugu Ariizumi;
- Masahiro Shimokawa;
- Yuya Hirasawa;
- Tomoyuki Ishiguro;
- Risako Suzuki;
- Nana Iriguchi;
- Toshiaki Tsurui
Publication type:
Article
Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1164724
By:
- Kazuyuki Hamada;
- Junya Isobe;
- Kouya Hattori;
- Masahiro Hosonuma;
- Yuta Baba;
- Masakazu Murayama;
- Yoichiro Narikawa;
- Hitoshi Toyoda;
- Eiji Funayama;
- Kohei Tajima;
- Midori Shida;
- Yuya Hirasawa;
- Toshiaki Tsurui;
- Hirotsugu Ariizumi;
- Tomoyuki Ishiguro;
- Risako Suzuki;
- Ryotaro Ohkuma;
- Yutaro Kubota;
- Takehiko Sambe;
- Mayumi Tsuji
Publication type:
Article
High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer.
Published in:
PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0226707
By:
- Ohkuma, Ryotaro;
- Yada, Erica;
- Ishikawa, Shumpei;
- Komura, Daisuke;
- Ishizaki, Hidenobu;
- Tamada, Koji;
- Kubota, Yutaro;
- Hamada, Kazuyuki;
- Ishida, Hiroo;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Satoh, Etsuko;
- Shida, Midori;
- Watanabe, Makoto;
- Onoue, Rie;
- Ando, Kiyohiro;
- Tsurutani, Junji;
- Yoshimura, Kiyoshi;
- Yokobori, Takehiko;
- Sasada, Tetsuro
Publication type:
Article
Chemotherapy combined with immune checkpoint inhibitors may overcome the detrimental effect of high neutrophil-to-lymphocyte ratio prior to treatment in esophageal cancer patients.
Published in:
Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1449941
By:
- Yuya Hirasawa;
- Yutaro Kubota;
- Emiko Mura;
- Risako Suzuki;
- Toshiaki Tsurui;
- Nana Iriguchi;
- Tomoyuki Ishiguro;
- Ryotaro Ohkuma;
- Masahiro Shimokawa;
- Hirotsugu Ariizumi;
- Atsushi Horiike;
- Satoshi Wada;
- Takeshi Yamashita;
- Tomotake Ariyoshi;
- Satoru Goto;
- Koji Otsuka;
- Masahiko Murakami;
- Yuji Kiuchi;
- Kiyoshi Yoshimura;
- Takuya Tsunoda
Publication type:
Article
Minimal contribution of the hepatic uptake transporter OATP1B1 to the inter-individual variability in SN-38 pharmacokinetics in cancer patients without severe renal failure.
Published in:
Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 3, p. 543, doi. 10.1007/s00280-021-04314-1
By:
- Tsuboya, Ayako;
- Kubota, Yutaro;
- Ishida, Hiroo;
- Ohkuma, Ryotaro;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Tsunoda, Takuya;
- Sasaki, Yasutsuna;
- Matsumoto, Natsumi;
- Kondo, Yusuke;
- Tomoda, Yukana;
- Kusuhara, Hiroyuki;
- Fujita, Ken-ichi
Publication type:
Article
Variants of carboxylesterase 1 have no impact on capecitabine pharmacokinetics and toxicity in capecitabine plus oxaliplatin treated-colorectal cancer patients.
Published in:
2020
By:
- Matsumoto, Natsumi;
- Kubota, Yutaro;
- Ishida, Hiroo;
- Sekido, Masae;
- Ohkuma, Ryotaro;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Tsunoda, Takuya;
- Ikusue, Toshikazu;
- Kobayashi, Kouji;
- Hisamatsu, Atsushi;
- Toshima, Hirokazu;
- Shimada, Ken;
- Fujita, Ken-ichi
Publication type:
journal article
High levels of human epididymis protein 4 mRNA and protein expression are associated with chemoresistance and a poor prognosis in pancreatic cancer.
Published in:
International Journal of Oncology, 2021, v. 58, n. 1, p. 57
By:
- Ohkuma, Ryotaro;
- Yada, Erica;
- Ishikawa, Shumpei;
- Komura, Daisuke;
- Kubota, Yutaro;
- Hamada, Kazuyuki;
- Horiike, Atsushi;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Shida, Midori;
- Watanabe, Makoto;
- Onoue, Rie;
- Ando, Kiyohiro;
- Tsurutani, Junji;
- Yoshimura, Kiyoshi;
- Sasada, Tetsuro;
- Aoki, Takeshi;
- Murakami, Masahiko;
- Norose, Tomoko
Publication type:
Article
Examination of endobronchial ultrasound-guided transbronchial needle aspiration using a puncture needle with a side trap.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89244-x
By:
- Miyazaki, Kazuhito;
- Hirasawa, Yuya;
- Aga, Masaharu;
- Aiko, Naoto;
- Hamakawa, Yusuke;
- Taniguchi, Yuri;
- Misumi, Yuki;
- Agemi, Yoko;
- Shimokawa, Tsuneo;
- Hayashi, Hiroyuki;
- Naoki, Katsuhiko;
- Okamoto, Hiroaki
Publication type:
Article
Increased Plasma Soluble PD-1 Concentration Correlates with Disease Progression in Patients with Cancer Treated with Anti-PD-1 Antibodies.
Published in:
Biomedicines, 2021, v. 9, n. 12, p. 1929, doi. 10.3390/biomedicines9121929
By:
- Ohkuma, Ryotaro;
- Ieguchi, Katsuaki;
- Watanabe, Makoto;
- Takayanagi, Daisuke;
- Goshima, Tsubasa;
- Onoue, Rie;
- Hamada, Kazuyuki;
- Kubota, Yutaro;
- Horiike, Atsushi;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Tsurutani, Junji;
- Yoshimura, Kiyoshi;
- Tsuji, Mayumi;
- Kiuchi, Yuji;
- Kobayashi, Shinichi;
- Tsunoda, Takuya;
- Wada, Satoshi
Publication type:
Article
Monocyte subsets associated with the efficacy of anti‑PD‑1 antibody monotherapy.
Published in:
Oncology Letters, 2023, v. 26, n. 3, p. N.PAG, doi. 10.3892/ol.2023.13967
By:
- Ohkuma, Ryotaro;
- Fujimoto, Yuki;
- Ieguchi, Katsuaki;
- Onishi, Nobuyuki;
- Watanabe, Makoto;
- Takayanagi, Daisuke;
- Goshima, Tsubasa;
- Horiike, Atsushi;
- Hamada, Kazuyuki;
- Ariizumi, Hirotsugu;
- Hirasawa, Yuya;
- Ishiguro, Tomoyuki;
- Suzuki, Risako;
- Iriguchi, Nana;
- Tsurui, Toshiaki;
- Sasaki, Yosuke;
- Homma, Mayumi;
- Yamochi, Toshiko;
- Yoshimura, Kiyoshi;
- Tsuji, Mayumi
Publication type:
Article
Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit.
Published in:
Cancer Science, 2024, v. 115, n. 3, p. 752, doi. 10.1111/cas.16061
By:
- Hosonuma, Masahiro;
- Hirasawa, Yuya;
- Kuramasu, Atsuo;
- Murayama, Masakazu;
- Narikawa, Yoichiro;
- Toyoda, Hitoshi;
- Baba, Yuta;
- Isobe, Junya;
- Funayama, Eiji;
- Tajima, Kohei;
- Shida, Midori;
- Hamada, Kazuyuki;
- Tsurui, Toshiaki;
- Ariizumi, Hirotsugu;
- Ishiguro, Tomoyuki;
- Suzuki, Risako;
- Ohkuma, Ryotaro;
- Kubota, Yutaro;
- Horiike, Atsushi;
- Sambe, Takehiko
Publication type:
Article
High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer.
Published in:
Oncology Reports, 2020, v. 44, n. 1, p. 252, doi. 10.3892/or.2020.7610
By:
- Ohkuma, Ryotaro;
- Yada, Erica;
- Ishikawa, Shumpei;
- Komura, Daisuke;
- Kubota, Yutaro;
- Hamada, Kazuyuki;
- Horiike, Atsushi;
- Ishiguro, Tomoyuki;
- Hirasawa, Yuya;
- Ariizumi, Hirotsugu;
- Shida, Midori;
- Watanabe, Makoto;
- Onoue, Rie;
- Ando, Kiyohiro;
- Tsurutani, Junji;
- Yoshimura, Kiyoshi;
- Sasada, Tetsuro;
- Aoki, Takeshi;
- Murakami, Masahiko;
- Norose, Tomoko
Publication type:
Article

Found: 17