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- Title
Pharmacoeconomic studies of bypassing agents in mild-tomoderate bleeding episodes in patients with hemophilia and inhibitors: a critical appraisal.
- Authors
De Paula, Erich V.; Ozelo, Margareth C.
- Abstract
The development of neutralizing antibodies against factor VIII and IX complicates the clinical management of patients with hemophilia, and adds significant costs to their treatment. For this reason, several formal economic analysis have been performed comparing treatment of mild and moderate bleeding episodes in these patients in an effort to determine whether one of the two available bypassing agents would be cost-effective compared with the other. Here we review and discuss the available evidence about the economic aspects of the alternatives for on-demand treatment of mild and moderate bleeding episodes for hemophilia patients with inhibitors.
- Subjects
HEMOPHILIA treatment; THERAPEUTICS; HEMOPHILIACS; BLOOD coagulation factors; HEMORRHAGE; BLOOD coagulation; BLOOD coagulation disorders; BLOOD coagulation factor VIII antibodies; CLINICAL trials; ECONOMICS
- Publication
Journal of Coagulation Disorders, 2010, Vol 2, Issue 2, p93
- ISSN
2041-7969
- Publication type
Article