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- Title
Efficacy of Ultrasound-Guided Needle Biopsy in the Diagnosis of Kikuchi-Fujimoto Disease.
- Authors
Park, Sang Gyu; Koo, Hye Ryoung; Jang, Kiseok; Myung, Jae Kyung; Song, Chang Myeon; Ji, Yong Bae; Park, Jeong Seon; Tae, Kyung
- Abstract
<bold>Objectives/hypothesis: </bold>Ultrasound-guided fine-needle aspiration cytology (US-FNAC) is a well-established procedure performed to establish the diagnosis of Kikuchi-Fujimoto disease (KFD). Ultrasound-guided core needle biopsy (US-CNB) is an alternative diagnostic tool for KFD. However, the efficacy of US-CNB is not well evaluated. This study aimed to evaluate the efficacy of US-CNB and compare it with that of US-FNAC in the diagnosis of KFD.<bold>Study Design: </bold>Retrospective cohort study.<bold>Methods: </bold>We analyzed 170 patients who were diagnosed with KFD between January 2009 and May 2019. US-FNAC, US-CNB, and excisional biopsy were performed in 47, 114, and 9 patients, respectively. Diagnostic accuracies of US-FNAC and US-CNB were analyzed and compared.<bold>Results: </bold>Of the 170 patients, 45 and 125 were men and women, respectively. The mean age was 26.9 ± 9.1 years. The most common symptom was cervical lymphadenopathy, followed by fever, headache, and myalgia. The diagnosis of KFD was established primarily by US-FNAC in 21 (44.7%) of the 47 patients, by US-CNB in 109 (95.6%) of the 114 patients, and by excisional biopsy in all 9 patients. There was no specific major complication related to US-FNAC and US-CNB.<bold>Conclusion: </bold>US-CNB can be considered safe and effective and used as the primary modality for the pathological diagnosis of KFD.<bold>Level Of Evidence: </bold>4. Laryngoscope, 131:E1519-E1523, 2021.
- Subjects
CORE needle biopsy; NEEDLE biopsy; DIAGNOSIS; LYMPHADENITIS; GROIN; RESEARCH; AXILLA; RESEARCH methodology; LYMPH nodes; MACROPHAGES; RETROSPECTIVE studies; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; NECK
- Publication
Laryngoscope, 2021, Vol 131, Issue 5, pE1519
- ISSN
0023-852X
- Publication type
journal article
- DOI
10.1002/lary.29160