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- Title
ANZTCT practice statement: sinusoidal obstruction syndrome/veno‐occlusive disease diagnosis and management.
- Authors
Fleming, Shaun; Scott, Ashleigh P.; Coutsouvelis, John; Fraser, Chris; Bajel, Ashish; Nelson, Adam; Conyers, Rachel; McEwan, Ashley; Yeung, David; Campion, Victoria; Teague, Lochie; McGuire, Matthew; Morris, Edward; Gabriel, Melissa; Wayte, Rebecca; Douglas, Genevieve; Chien, Nicole; Hamad, Nada
- Abstract
Sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD) is a life‐threatening complication which can develop after haemopoietic stem cell transplantation (HSCT) and some antibody–drug conjugates. Several SOS/VOD diagnostic and management guidelines exist, with the most recent and refined being the European Society for Blood and Marrow Transplantation adult and paediatric guidelines. Timely diagnosis and effective management (including the availability of therapeutic options) significantly contribute to improved patient outcomes. In Australia and New Zealand, there is variability in clinical practice and access to SOS/VOD therapies. This review aims to summarise the current evidence for SOS/VOD diagnosis, prevention and treatment and to provide recommendations for SOS/VOD in the context of contemporary Australasian HSCT clinical practice.
- Subjects
AUSTRALIA; LUNG disease diagnosis; LUNG disease prevention; THERAPEUTIC use of monoclonal antibodies; MEDICAL protocols; HEMATOPOIETIC stem cell transplantation; BLOOD; DISEASE management; PEDIATRICS; LUNG diseases; HEPATIC veno-occlusive disease; BONE marrow transplantation
- Publication
Internal Medicine Journal, 2024, Vol 54, Issue 9, p1548
- ISSN
1444-0903
- Publication type
Article
- DOI
10.1111/imj.16453