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- Title
Combination of Reaction and Separation in Heterogeneous Catalytic Hydrogenation of Ethylformate.
- Authors
Martin, Gerson; Pereira, Carla; Pettersson, Frank; Saxén, Henrik; Murzin, Dmitry Y.; Rodrigues, Alírio; Salmi, Tapio
- Abstract
Continuous hydrogenation reaction of ethyl benzoylformate was studied over a (-)-cinchonidine (CD)-modified Pt/Al2O3 catalyst. The catalyst showed a good stability, and high enantioselectivity was achieved in the fixed-bed reactor. Chromatographic separation of ( R)- and ( S)-ethyl mandelate originating from a post-continuous hydrogenation reaction of ethyl benzoylformate over the (-)-CD-modified Pt/Al2O3 catalyst was investigated in the same reaction mixture. A commercial column filled with a chiral selector resin was chosen as a perspective preparative-scale adsorbent. Since adsorption equilibrium isotherms were linear within the entire investigated range of concentrations, they were determined by pulse experiments for the isomers present in a post-reaction mixture. Breakthrough curves were measured and described successfully by the dispersive plug-flow model with linear driving force approximation.
- Subjects
HYDROGENATION; ADDITION reactions; CATALYTIC dehydrogenation; CATALYTIC hydrogenation; GREEN diesel fuels
- Publication
Chemical Engineering & Technology, 2015, Vol 38, Issue 5, p804
- ISSN
0930-7516
- Publication type
Article
- DOI
10.1002/ceat.201400649