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- Title
Role of Chloramphenicol Reduction Products in Aplastic Anemia.
- Authors
Pazdernik, Thomas L.; Corbett, Michael D.
- Abstract
Oral administration of chloramphenicol did not significantly alter the early stage of chronic hypoplastic marrow failure induced by busulfan. Chloramphenicol reduction products were most suppressive to antigen-reactive cells detected by the Mishell-Dutton plaque-forming cell assay. This reduction in immunocompetence may be an important parameter in the initial phases of the etiology of chloramphenicol-induced aplastic anemia. Copyright © 1980 S. Karger AG, Basel
- Publication
Pharmacology, 1980, Vol 20, Issue 2, p87
- ISSN
0031-7012
- Publication type
Article
- DOI
10.1159/000137348