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- Title
Propolis "bee glue" as therapeutic and protective effect on diabetic rabbits.
- Authors
Asmaa, M. F.; Essamy, D. E.
- Abstract
Propolis is a honeybee product that has gained popularity in alternative medicine, due to its biological properties and it has been intensively used in health supplement foods. This study was carried out to investigate the effect of propolis on some biochemical parameters in alloxan-induced diabetic rabbits. Diabetes was induced in all rabbits, except control and propolis control, by a single dose of Alloxan(150 mg/kg).Rabbits with glycaemia were treated with alcoholic extract of propolis(50mg/kg/day) orally for 10 days marked significant increase (p<0.05) in the biochemical values, which including glucose, cholesterol, urea and creatininewere recorded in comparison with the control and diabetic groups. The protective and therapeutic groups showed significant decrease (P<0.05) in glucose, cholesterol, urea and creatinine in comparison with the diabetic group. While the propolishas no significant effect on the level of blood glucose, cholesterol, urea and creatinine with control group. Generally, the gradual improvement in blood values was noticed forpropolis (50mg/kg) and administration dose had a potent antihyperglycemic effect. In conclusion, the results suggest that propolis could potentially contribute for the treatment of diabetes mellitus.
- Subjects
ALLOXAN; DIABETES; URIC acid; PROPOLIS; BEE products
- Publication
Annals of Agricultural Science Moshtohor, 2017, Vol 55, Issue 2, p355
- ISSN
1110-0419
- Publication type
Article