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- Title
Kikuchi-Fujimoto Disease: the First Reported Case in Croatia.
- Authors
Kotromanović, Zeljko; Mihalj, Hrvoje; Kotromanović, Zdenka; Raje, Jasmina; Vceva, Andrijana; Mihalj, Martina; Zubcic, Zeljko; Birtic, Darija
- Abstract
Kikuchi-Fujimoto disease (KFD) is an extremely rare disease known to have a worldwide distribution with higher prevalence among Japanese and other Asiatic individuals. KFD presents as benign and self-limited disorder, character-ized by regional cervical lymphadenopathy with tenderness, usually accompanied with mild to high fever and night sweats. Less frequent symptoms include weight loss, nausea, vomiting and sore throat. Final diagnosis can only be deter-mined on the basis of typical morphological changes in the lymph node, therefore lymph node biopsy is crucial for prov-ing the diagnosis. Here we present a 16-year-old, native Croatian, Caucasian girl with KFD, as a first case of KFD re-ported in Croatia. We suggest that this disease should be considered as a possible cause of fever of the unknown origin followed by lymphadenopathy. Kikuchi-Fujimoto bolesti (KFB) je izuzetno rijetka bolest, koja se pojavljuje u cijelom svijetu s većom učestalošću među japanskom i drugim azijskim populacijama. KFB je dobroćudni, samo-ograničavajući poremećaj kojeg karakte-rizira regionalna cervikalna limfadenopatija, najčešće uz blagu vrućicu i noćno znojenje. Manje česti simptomi su gubi-tak težine, mučnina, povraćanje i bolovi u grlu. Konačna dijagnoza se određuje na temelju tipičnih morfoloških promje-na u zahvaćenom limfnom čvoru, stoga je biopsija limfnog čvora presudna za potvrdu dijagnoze. Ovdje predstavljamo šesnaestogodišnju djevojčicu, autohtonu hrvaticu, bijele rase s dokazanom KFB, kao prvi zabilježeni slučaj KFB-i u Hrvatskoj. Također, ovdje želimo istaknuti da KFB treba razmotriti kao mogući uzrok vrućice nepoznatog porijekla praćene limfadenopatijom.
- Subjects
RARE diseases; ASIANS; LYMPHADENITIS; LYMPHATIC diseases; FEVER; LYMPH circulation disorders; PATIENTS; DISEASES
- Publication
Collegium Antropologicum, 2013, Vol 37, Issue 2, p607
- ISSN
0350-6134
- Publication type
Article