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Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems.
Published in:
Pharmaceutics, 2019, v. 11, n. 2, p. 70, doi. 10.3390/pharmaceutics11020070
By:
- Rudnik-Jansen, Imke;
- Woike, Nina;
- de Jong, Suzanne;
- Versteeg, Sabine;
- Kik, Marja;
- Emans, Pieter;
- Mihov, George;
- Thies, Jens;
- Eijkelkamp, Niels;
- Tryfonidou, Marianna;
- Creemers, Laura
Publication type:
Article
Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5023, doi. 10.1172/JCI66241
By:
- Huijing Wang;
- Heijnen, Cobi J.;
- van Velthoven, Cindy T.J.;
- Willemen, Hanneke L.D.M.;
- Yoshihiro Ishikawa;
- Xinna Zhang;
- Anil K. Sood;
- Vroon, Anne;
- Eijkelkamp, Niels;
- Kavelaars, Annemieke
Publication type:
Article
Sialic Acid-Engineered IL4–10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 2, p. 1, doi. 10.1007/s11095-019-2744-y
By:
- Steen-Louws, Cristine;
- Boross, Peter;
- Prado, Judith;
- Meeldijk, Jan;
- Langenhorst, Jurgen B.;
- Huitema, Alwin D. R.;
- den Hartog, Marcel T.;
- Boon, Louis;
- Lafeber, Floris P. J. G.;
- Hack, C. Erik;
- Eijkelkamp, Niels;
- Popov-Celeketic, Jelena
Publication type:
Article
Identification of FAM173B as a protein methyltransferase promoting chronic pain.
Published in:
PLoS Biology, 2018, v. 16, n. 2, p. 1, doi. 10.1371/journal.pbio.2003452
By:
- Willemen, Hanneke L. D. M.;
- Kavelaars, Annemieke;
- Prado, Judith;
- Maas, Mirjam;
- Versteeg, Sabine;
- Nellissen, Lara J. J.;
- Tromp, Jeshua;
- Gonzalez Cano, Rafael;
- Zhou, Wenjun;
- Jakobsson, Magnus E.;
- Małecki, Jędrzej;
- Posthuma, George;
- Habib, Abdella M.;
- Heijnen, Cobi J.;
- Falnes, Pål Ø.;
- Eijkelkamp, Niels
Publication type:
Article
Effects of mesenchymal stem cells and heparan sulfate mimetics on urethral function and vaginal wall biomechanics in a simulated rat childbirth injury model.
Published in:
International Urogynecology Journal, 2023, v. 34, n. 7, p. 1635, doi. 10.1007/s00192-022-05439-4
By:
- Janssen, Kristine;
- van Ruiten, Geertruida W.;
- Eijkelkamp, Niels;
- Damaser, Margot S.;
- van der Vaart, Carl H.
Publication type:
Article
Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128830
By:
- Koenig, Jennifer;
- Werdehausen, Robert;
- Linley, John E.;
- Habib, Abdella M.;
- Vernon, Jeffrey;
- Lolignier, Stephane;
- Eijkelkamp, Niels;
- Zhao, Jing;
- Okorokov, Andrei L.;
- Woods, C. Geoffrey;
- Wood, John N.;
- Cox, James J.
Publication type:
Article
Significant Determinants of Mouse Pain Behaviour.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104458
By:
- Minett, Michael S.;
- Eijkelkamp, Niels;
- Wood, John N.
Publication type:
Article
Correction: Significant Determinants of Mouse Pain Behaviour.
Published in:
2021
By:
- Minett, Michael S.;
- Eijkelkamp, Niels;
- Wood, John N.
Publication type:
Correction Notice
GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 6, p. 2138, doi. 10.1523/JNEUROSCI.5752-09.2010
By:
- Eijkelkamp, Niels;
- Heijnen, Cobi J.;
- Willemen, Hanneke L. D. M.;
- Deumens, Ronald;
- Joosten, Elbert A. J.;
- Kleibeuker, Wendy;
- den Hartog, Ilona J. M.;
- van Velthoven, Cindy T. J.;
- Nijboer, Cora;
- Nassar, Mohammed A.;
- Dorn II, Gerald W.;
- Wood, John N.;
- Kavelaars, Annemieke
Publication type:
Article
G protein-coupled receptor kinase 2 positively regulates epithelial cell migration.
Published in:
EMBO Journal, 2008, v. 27, n. 8, p. 1206, doi. 10.1038/emboj.2008.55
By:
- Penela, Petronila;
- Ribas, Catalina;
- Aymerich, Ivette;
- Eijkelkamp, Niels;
- Barreiro, Olga;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke;
- Sánchez-Madrid, Francisco;
- Mayor Jr., Federico
Publication type:
Article
Mechanical allodynia.
Published in:
Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 1, p. 133, doi. 10.1007/s00424-014-1532-0
By:
- Lolignier, Stéphane;
- Eijkelkamp, Niels;
- Wood, John
Publication type:
Article
Identifying disrupted biological factors and patient-tailored interventions for chronic fatigue in adolescents and young adults with Q-Fever Fatigue Syndrome, Chronic Fatigue Syndrome and Juvenile Idiopathic Arthritis (QFS-study): study protocol for a randomized controlled trial with single-subject experimental case series design.
Published in:
Trials, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13063-022-06620-2
By:
- Vroegindeweij, Anouk;
- Swart, Joost F.;
- Houtveen, Jan;
- Eijkelkamp, Niels;
- van de Putte, Elise M.;
- Wulffraat, Nico M.;
- Nijhof, Sanne L.
Publication type:
Article
Neurological perspectives on voltage-gated sodium channels.
Published in:
Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2585, doi. 10.1093/brain/aws225
By:
- Eijkelkamp, Niels;
- Linley, John E.;
- Baker, Mark D.;
- Minett, Michael S.;
- Cregg, Roman;
- Werdehausen, Robert;
- Rugiero, François;
- Wood, John N.
Publication type:
Article
Relaxin receptor deficiency promotes vascular inflammation and impairs outward remodeling in arteriovenous fistulas.
Published in:
FASEB Journal, 2018, v. 32, n. 11, p. 6293, doi. 10.1096/fj.201800437R
By:
- Bezhaeva, Taisiya;
- de Vries, Margreet R.;
- Geelhoed, Wouter J.;
- van der Veer, Eric P.;
- Versteeg, Sabine;
- van Alem, Carla M. A.;
- Voorzaat, Bram M.;
- Eijkelkamp, Niels;
- van der Bogt, Koen E.;
- Agoulnik, Alexander I.;
- van Zonneveld, Anton-Jan;
- Quax, Paul H. A.;
- Rotmans, Joris I.
Publication type:
Article
Divergent roles of immune cells and their mediators in pain.
Published in:
Rheumatology, 2018, v. 57, n. 3, p. 429, doi. 10.1093/rheumatology/kex308
By:
- Raoof, Ramin;
- Willemen, Hanneke L D M;
- Eijkelkamp, Niels
Publication type:
Article
Feasibility of quantitative sensory testing in juvenile idiopathic arthritis.
Published in:
Pediatric Rheumatology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12969-022-00715-5
By:
- Mensink, Maarten O.;
- Eijkelkamp, Niels;
- Veldhuijzen, Dieuwke S.;
- Wulffraat, Nico M.
Publication type:
Article
Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00592
By:
- Hui-Jing Wang;
- Han-Xin Gu;
- Niels Eijkelkamp;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke
Publication type:
Article
G Protein-Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p38 Signaling.
Published in:
Molecular Medicine, 2012, v. 18, n. 4, p. 556, doi. 10.2119/molmed.2011.00398
By:
- Eijkelkamp, Niels;
- Heijnen, Cobi J.;
- Carbajal, Anibal Garza;
- Willemen, Hanneke L. D. M.;
- Wang, Huijing;
- Minett, Michael S.;
- Wood, John N.;
- Schedlowski, Manfred;
- Dantzer, Robert;
- Kelley, Keith W.;
- Kavelaars, Annemieke
Publication type:
Article
Amyloid Proteins and Peripheral Neuropathy.
Published in:
Cells (2073-4409), 2020, v. 9, n. 6, p. 1553, doi. 10.3390/cells9061553
By:
- Asiri, Mohammed M. H.;
- Engelsman, Sjoukje;
- Eijkelkamp, Niels;
- Höppener, Jo W. M.
Publication type:
Article
Neuro-immune interactions in paclitaxel-induced peripheral neuropathy.
Published in:
Acta Oncologica, 2021, v. 60, n. 10, p. 1369, doi. 10.1080/0284186X.2021.1954241
By:
- Vermeer, Cornelia J. C.;
- Hiensch, Anouk E.;
- Cleenewerk, Laurence;
- May, Anne M.;
- Eijkelkamp, Niels
Publication type:
Article
A role for G protein-coupled receptor kinase 2 in mechanical allodynia.
Published in:
European Journal of Neuroscience, 2007, v. 25, n. 6, p. 1696, doi. 10.1111/j.1460-9568.2007.05423.x
By:
- Kleibeuker, Wendy;
- Ledeboer, Annemarie;
- Eijkelkamp, Niels;
- Watkins, Linda R.;
- Maier, Steven F.;
- Zijlstra, Jitske;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke
Publication type:
Article
Dorsal Root Ganglia Macrophages Maintain Osteoarthritis Pain.
Published in:
Journal of Neuroscience, 2021, v. 41, n. 39, p. 8249, doi. 10.1523/JNEUROSCI.1787-20.2021
By:
- Raoof, Ramin;
- Gil, Christian Martin;
- Lafeber, Floris P. J. G.;
- de Visser, Huub;
- Prado, Judith;
- Versteeg, Sabine;
- Pascha, Mirte N.;
- Heinemans, Anne L. P.;
- Adolfs, Youri;
- Pasterkamp, Jeroen;
- Wood, John N.;
- Mastbergen, Simon C.;
- Eijkelkamp, Niels
Publication type:
Article
CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.
Published in:
Journal of Neuroscience, 2016, v. 36, n. 43, p. 11074, doi. 10.1523/JNEUROSCI.3708-15.2016
By:
- Krukowski, Karen;
- Eijkelkamp, Niels;
- Laumet, Geoffroy;
- Hack, C. Erik;
- Yan Li;
- Dougherty, Patrick M.;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke
Publication type:
Article
Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.
Published in:
Journal of Neurochemistry, 2008, v. 104, n. 4, p. 979, doi. 10.1111/j.1471-4159.2007.05023.x
By:
- Kleibeuker, Wendy;
- Jurado-Pueyo, Maria;
- Murga, Cristina;
- Eijkelkamp, Niels;
- Mayor Jr, Federico;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke
Publication type:
Article
Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model.
Published in:
Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03368-7
By:
- Warmink, Kelly;
- Rios, Jaqueline L.;
- Varderidou-Minasian, Suzy;
- Torres-Torrillas, Marta;
- van Valkengoed, Devin R.;
- Versteeg, Sabine;
- Eijkelkamp, Niels;
- Weinans, Harrie;
- Korthagen, Nicoline M.;
- Lorenowicz, Magdalena J.
Publication type:
Article
IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain.
Published in:
Journal of Neuroscience, 2016, v. 38, n. 28, p. 7353, doi. 10.1523/JNEUROSCI.0092-16.2016
By:
- Eijkelkamp, Niels;
- Steen-Louws, Cristine;
- Hartgring, Sarita A. Y.;
- Willemen, Hanneke L. D. M.;
- Prado, Judith;
- Lafeber, Floris P. J. G.;
- Heijnen, Cobi J.;
- Hack, C. E.;
- van Roon, Joel A. G.;
- Kavelaars, Annemieke
Publication type:
Article
Low Nociceptor GRK2 Prolongs Prostaglandin E2 Hyperalgesia via Biased cAMP Signaling to Epac/Rap1, Protein Kinase Cϵ, and MEK/ERK.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 38, p. 12806, doi. 10.1523/JNEUROSCI.3142-10.2010
By:
- Eijkelkamp, Niels;
- Wang, Huijing;
- Garza-Carbajal, Anibal;
- Willemen, Hanneke L. D. M.;
- Zwartkruis, Fried J.;
- Wood, John N.;
- Dantzer, Robert;
- Kelley, Keith W.;
- Heijnen, Cobi J.;
- Kavelaars, Annemieke
Publication type:
Article

Found: 27

Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems.

Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain.

Sialic Acid-Engineered IL4–10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.

Identification of FAM173B as a protein methyltransferase promoting chronic pain.

Effects of mesenchymal stem cells and heparan sulfate mimetics on urethral function and vaginal wall biomechanics in a simulated rat childbirth injury model.

Regulation of Na<sub>v</sub>1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia.

Significant Determinants of Mouse Pain Behaviour.

Correction: Significant Determinants of Mouse Pain Behaviour.

GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain.

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration.

Mechanical allodynia.

Neurological perspectives on voltage-gated sodium channels.

Relaxin receptor deficiency promotes vascular inflammation and impairs outward remodeling in arteriovenous fistulas.

Divergent roles of immune cells and their mediators in pain.

Feasibility of quantitative sensory testing in juvenile idiopathic arthritis.

Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor.

G Protein-Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p38 Signaling.

Amyloid Proteins and Peripheral Neuropathy.

Neuro-immune interactions in paclitaxel-induced peripheral neuropathy.

A role for G protein-coupled receptor kinase 2 in mechanical allodynia.

Dorsal Root Ganglia Macrophages Maintain Osteoarthritis Pain.

CD8<sup>+</sup> T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.

Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.

Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model.

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain.

Low Nociceptor GRK2 Prolongs Prostaglandin E<sub>2</sub> Hyperalgesia via Biased cAMP Signaling to Epac/Rap1, Protein Kinase Cϵ, and MEK/ERK.