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- Title
AVALIAÇÃO DO PERFIL LIPÍDICO E HEPÁTICO DE RATOS WISTAR ALIMENTADOS COM DIETA HIPERCALÓRICA E SUPLEMENTADOS COM BIXINA.
- Authors
da Silva, Patrícia Ferreira; Lopes Haidamus, Leandro; de Carvalho, Wanderson Luís
- Abstract
The hypercaloric diet is an important inducer of dyslipidemias and, in turn, causes damage to health, especially to the liver. This work was developed with the objective of testing bixin, a carotenoid present in the seeds of annatto (Bixa orellana L.), verifying its side effects on lipid and hepatic metabolism in rats. Fifteen animals were randomly divided into control (C), hypercaloric (H) and hypercaloric groups with bixin (H+B) with five animals each, receiving feed ad libtum during the period of 25 days. The diet with bixin promoted weight maintenance, decreased ALT levels, decreased triglyceride levels and increased HDL-c. The liver histopathology showed a decrease in fat degeneration, inflammatory infiltrate and cell injury.
- Publication
Colloquium Vitae, 2018, Vol 10, Issue 2, p24
- ISSN
1984-6436
- Publication type
Article
- DOI
10.5747/cv.2018.v10.n2.v227