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- Title
Characterizing weekly self-reported antihypertensive medication nonadherence across repeated occasions.
- Authors
Voils, Corrine I.; King, Heather A.; Neelon, Brian; Hoyle, Rick H.; Reeve, Bryce B.; Maciejewski, Matthew L.; Yancy Jr, William S.
- Abstract
Background: Little is known about weekly variability in medication nonadherence both between and within persons. Purpose: To characterize medication nonadherence across repeated, closely spaced occasions. Methods: This prospective cohort study comprised four unannounced telephone assessment occasions, each separated by approximately 2 weeks. On each occasion, adult outpatients taking at least a single antihypertensive medication completed a measure of extent of, and reasons for, nonadherence. Results: Two hundred and sixty-one participants completed 871 (83%) of 1,044 occasions. Nonadherence was reported on 152 (17.5%) of 871 occasions by 93 (36%) of 261 participants. The most commonly endorsed reasons for nonadherence were forgetting (39.5%), being busy (23.7%), and traveling (19.7%). Among 219 participants completing at least three occasions, 50% of the variability in extent of nonadherence was a result of within-person fluctuations, and 50% was a result of between-person differences. Conclusion: Interventions to reduce nonadherence should be informed by variability in the extent of nonadherence and specific reasons for nonadherence.
- Subjects
ANTIHYPERTENSIVE agents; MEDICATION therapy management; DRUG utilization; COHORT analysis; THERAPEUTICS
- Publication
Patient Preference & Adherence, 2014, Vol 8, p643
- ISSN
1177-889X
- Publication type
Article
- DOI
10.2147/PPA.S60715