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- Title
Three-dimensional verification of ¹²⁵I seed stability after permanent implantation in the parotid gland and periparotid region.
- Authors
Yi Fan; Ming-Wei Huang; Lei Zheng; Yi-Jiao Zhao; Jian-Guo Zhang; Fan, Yi; Huang, Ming-Wei; Zheng, Lei; Zhao, Yi-Jiao; Zhang, Jian-Guo
- Abstract
<bold>Objective: </bold>To evaluate seed stability after permanent implantation in the parotid gland and periparotid region via a three-dimensional reconstruction of CT data.<bold>Material and Methods: </bold>Fifteen patients treated from June 2008 to June 2012 at Peking University School and Hospital of Stomatology for parotid gland tumors with postoperative adjunctive (125)I interstitial brachytherapy were retrospectively reviewed in this study. Serial CT data were obtained during follow-up. Mimics and Geomagic Studio software were used for seed reconstruction and stability analysis, respectively.<bold>Results: </bold>Seed loss and/or migration outside of the treated area were absent in all patients during follow-up (23-71 months). Total seed cluster volume was maximized on day 1 post-implantation due to edema and decreased significantly by an average of 13.5 % (SD = 9.80 %; 95 % CI, 6.82-17.68 %) during the first two months and an average of 4.5 % (SD = 3.60 %; 95 % CI, 2.29-6.29 %) during the next four months. Volume stabilized over the subsequent six months.<bold>Conclusions: </bold>(125)I seed number and location were stable with a general volumetric shrinkage tendency in the parotid gland and periparotid region. Three-dimensional seed reconstruction of CT images is feasible for visualization and verification of implanted seeds in parotid brachytherapy.
- Subjects
INTERSTITIAL brachytherapy; PAROTID glands; RETROSPECTIVE studies; FOLLOW-up studies (Medicine); EDEMA; MEDICAL imaging systems; THREE-dimensional imaging; CANCER radiotherapy; IODINE radioisotopes; COMPUTED tomography; DIAGNOSTIC imaging; COMPUTERS in medicine; PAROTID gland tumors; RADIOISOTOPE brachytherapy; THERAPEUTICS
- Publication
Radiation Oncology, 2015, Vol 10, Issue 1, p1
- ISSN
1748-717X
- Publication type
journal article
- DOI
10.1186/s13014-015-0552-z