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- Title
Effect of Influenza Vaccination on Risk of Coronavirus Disease 2019: A Prospective Cohort Study of 46 000 Healthcare Workers.
- Authors
Kristensen, Jonas Henrik; Hasselbalch, Rasmus Bo; Pries-Heje, Mia; Nielsen, Pernille Brok; Knudsen, Andreas Dehlbæk; Fogh, Kamille; Norsk, Jakob Boesgaard; Eiken, Aleksander; Andersen, Ove; Fischer, Thea Kølsen; Jensen, Claus Antonio Juul; Torp-Pedersen, Christian; Rungby, Jørgen; Ditlev, Sisse Bolm; Hageman, Ida; Møgelvang, Rasmus; Gybel-Brask, Mikkel; Dessau, Ram Benny; Sørensen, Erik; Harritshøj, Lene
- Abstract
Background The purpose of this study was to assess whether influenza vaccination has an impact on the risk of coronavirus disease 2019 (COVID-19). Methods A cohort of 46 112 healthcare workers were tested for antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and filled in a survey on COVID-19 symptoms, hospitalization, and influenza vaccination. Results The risk ratio of hospitalization due to SARS-CoV-2 for influenza vaccinated compared with unvaccinated participants was 1.00 for the seasonal vaccination in 2019/2020 (confidence interval,.56–1.78, P = 1.00). Likewise, no clinical effect of influenza vaccination on development of antibodies against SARS-CoV-2 was found. Conclusions The present findings indicate that influenza vaccination does not affect the risk of SARS-CoV-2 infection or COVID-19.
- Publication
Journal of Infectious Diseases, 2022, Vol 226, Issue 1, p6
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1093/infdis/jiac001