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- Title
Generation of bovine transgenics using somatic cell nuclear transfer.
- Authors
Hodges, Craig A.; Stice, Steven L.
- Abstract
The ability to produce transgenic animals through the introduction of exogenous DNA has existed for many years. However, past methods available to generate transgenic animals, such as pronuclear microinjection or the use of embryonic stem cells, have either been inefficient or not available in all animals, bovine included. More recently somatic cell nuclear transfer has provided a method to create transgenic animals that overcomes many deficiencies present in other methods. This review summarizes the benefits of using somatic cell nuclear transfer to create bovine transgenics as well as the possible opportunities this method creates for the future.
- Subjects
TRANSGENIC animals; BOVINE somatotropin; GENETIC engineering; SOMATIC cells; REPRODUCTIVE health; EMBRYOLOGY; ENDOCRINOLOGY; BIOLOGY
- Publication
Reproductive Biology & Endocrinology, 2003, Vol 1, p81
- ISSN
1477-7827
- Publication type
Article
- DOI
10.1186/1477-7827-1-81