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- Title
Feasibility of a 20-gauge ProCore needle in EUS-guided subepithelial tumor sampling: a prospective multicenter study.
- Authors
Do Hoon Kim; Gwang Ha Kim; Chang Min Cho; Chang Hwan Park; Soo-Young Na; Tae Hyeon Kim; Yu Kyung Cho; Ji Hyun Kim; Dong-Wan Seo; Kim, Do Hoon; Kim, Gwang Ha; Cho, Chang Min; Park, Chang Hwan; Na, Soo-Young; Kim, Tae Hyeon; Cho, Yu Kyung; Kim, Ji Hyun; Seo, Dong-Wan; Korean EUS Study Group
- Abstract
<bold>Background: </bold>Endoscopic ultrasonography-guided fine-needle biopsy (EUS-FNB) may facilitate tissue acquisition for a definitive diagnosis of gastrointestinal subepithelial tumors (SETs). This study aimed to determine the diagnostic yield of EUS-FNB using a novel 20-gauge ProCore needle with a coiled sheath in tissue sampling of gastrointestinal SETs.<bold>Methods: </bold>Between July 2016 and February 2017, 39 patients with gastrointestinal SETs were prospectively recruited from six university hospitals in Korea. Hypoechoic SETs ≥2 cm in size and originating from the submucosal and/or muscularis propria layer under EUS were eligible. This study was registered on ClinicalTrials.gov (NCT02884154).<bold>Results: </bold>A total of 36 patients were included in the final analyses. EUS-FNB was diagnostic in 88.9% of SETs. Tissue adequacy was judged as optimal in 97.2% of FNB specimens according to on-site visual evaluation by endosonographers, and in 88.9% of specimens according to pathologists. A macroscopically optimal core sample was obtained with two needle passes in 94.4% of cases. Technical failure rate was encountered in two cases (5.6%) after two needle passes. There were two cases (5.6%) of bleeding, which was managed endoscopically.<bold>Conclusions: </bold>EUS-FNB using a 20-gauge ProCore needle is a technically feasible and effective modality for histopathologic diagnosis of gastrointestinal SETs, providing adequate core samples with fewer needle passes; ClinicalTrials.gov number, NCT02884154.
- Subjects
GASTROINTESTINAL agents; GASTROINTESTINAL diseases; HISTOPATHOLOGY; DIAGNOSIS; CLINICAL trials; ENDOSCOPY
- Publication
BMC Gastroenterology, 2018, Vol 18, p1
- ISSN
1471-230X
- Publication type
journal article
- DOI
10.1186/s12876-018-0880-1