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- Title
Self-Deprotonation and Colorization of 1,3-Bis(dicyanomethylidene)indan in Polar Media: A Facile Route to a Minimal Polymethine Dye for NIR Fluorescence Imaging.
- Authors
Heo, Jeongyun; Lim, Chang-Keun; Whang, Dong Ryeol; Shin, Jiyoung; Jeong, Seo Young; Park, Soo Young; Kwon, Ick Chan; Kim, Sehoon
- Abstract
Colorless 1,3-bis(dicyanomethylidene)indan is an organic acid (p Ka≈3.0) that turns blue in polar media owing to self-deprotonation. Moreover, its colored conjugate base shows potential as a minimal anionic polymethine dye for probing biomolecules in cells and in vivo through noncovalent complexation and near-infrared fluorescence signaling.
- Publication
Chemistry - A European Journal, 2012, Vol 18, Issue 28, p8699
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201103042