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- Title
Immunomodulatory Effects of Green Tea Polyphenols †.
- Authors
Wang, Shuzhen; Li, Zhiliang; Ma, Yuting; Liu, Yan; Lin, Chi-Chen; Li, Shiming; Zhan, Jianfeng; Ho, Chi-Tang
- Abstract
Green tea and its bioactive components, especially polyphenols, possess many health-promoting and disease-preventing benefits, especially anti-inflammatory, antioxidant, anticancer, and metabolic modulation effects with multi-target modes of action. However, the effect of tea polyphenols on immune function has not been well studied. Moreover, the underlying cellular and molecular mechanisms mediating immunoregulation are not well understood. This review summarizes the recent studies on the immune-potentiating effects and corresponding mechanisms of tea polyphenols, especially the main components of (–)-epigallocatechin-3-gallate (EGCG) and (–)-epicatechin-3-gallate (ECG). In addition, the benefits towards immune-related diseases, such as autoimmune diseases, cutaneous-related immune diseases, and obesity-related immune diseases, have been discussed.
- Subjects
EPIGALLOCATECHIN gallate; GREEN tea; POLYPHENOLS; BIOACTIVE compounds; AUTOIMMUNE diseases; IMMUNOLOGIC diseases; TEA
- Publication
Molecules, 2021, Vol 26, Issue 12, p3755
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules26123755