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- Title
Can we make Chitosan by Enzymatic Deacetylation of Chitin?
- Authors
Harmsen, Rianne A. G.; Tuveng, Tina R.; Antonsen, Simen G.; Eijsink, Vincent G. H.; Sørlie, Morten
- Abstract
Chitin, an insoluble linear polymer of β-1,4-N-acetyl-d-glucosamine (GlcNAc; A), can be converted to chitosan, a soluble heteropolymer of GlcNAc and d-glucosamine (GlcN; D) residues, by partial deacetylation. In nature, deacetylation of chitin is catalyzed by enzymes called chitin deacetylases (CDA) and it has been proposed that CDAs could be used to produce chitosan. In this work, we show that CDAs can remove up to approximately 10% of N-acetyl groups from two different (α and β) chitin nanofibers, but cannot produce chitosan.
- Subjects
CHITIN; CHITOSAN; LINEAR polymers; DEACETYLATION
- Publication
Molecules, 2019, Vol 24, Issue 21, p3862
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules24213862