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- Title
Norovirus strains in patients with acute gastroenteritis in rural and low-income urban areas in northern Brazil.
- Authors
Tinker, Rory J.; da Costa, Antonio Charlys; Tahmasebi, Roozbeh; Milagres, Flavio Augusto de Pádua; dos Santos Morais, Vanessa; Pandey, Ramendra Pati; José-Abrego, Alexis; Brustulin, Rafael; Rodrigues Teles, Maria da Aparecida; Cunha, Mariana Sequetin; Araújo, Emerson Luiz Lima; Gómez, Mariela Martínez; Deng, Xutao; Delwart, Eric; Sabino, Ester Cerdeira; Leal, Elcio; Luchs, Adriana
- Abstract
From 2010-2016, a total of 251 stool samples were screened for norovirus using next-generation sequencing (NGS) followed by phylogenetic analysis to investigate the genotypic diversity of noroviruses in rural and low-income urban areas in northern Brazil. Norovirus infection was detected in 19.9% (50/251) of the samples. Eight different genotypes were identified: GII.4_Sydney[P31] (64%, 32/50), GII.6[P7] (14%, 7/50), GII.17[P17] (6%, 3/50), GII.1[P33] (6%, 3/50), GII.3[P16] (4%, 2/50), GII.2[P16] (2%, 1/50), GII.2[P2] (2%, 1/50), and GII.4_New Orleans[P4] (2%, 1/50). Distinct GII.6[P7] variants were recognized, indicating the presence of different co-circulating strains. Elucidating norovirus genetic diversity will improve our understanding of their potential health burden, in particular for the GII.4_Sydney[P31] variant.
- Publication
Archives of Virology, 2021, Vol 166, Issue 3, p905
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-020-04944-5