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- Title
Laparoscopic Hepatectomy (with or without Robotic Assistance) versus Radiofrequency Ablation as a Minimally Invasive Treatment for Very Early-Stage or Early-Stage Hepatocellular Carcinoma.
- Authors
Chong, Charing Ching-Ning; Lee, Kit-Fai; Chu, Cheuk-Man; Chan, Anthony Wing-Hung; Yu, Simon Chun-Ho; Lai, Paul Bo-San
- Abstract
Background: The advantages of radiofrequency ablation (RFA) over hepatectomy as a treatment for early-stage hepatocellular carcinoma (HCC) include reduced morbidity and more rapid recovery. Although minimally invasive surgery provides similar benefits, few studies have compared the long-term oncological outcomes of these techniques. This study aimed to compare the outcomes of minimally invasive hepatectomy (MIH) and RFA. Methods: Patients who underwent MIH or RFA for HCC between January 2005 and January 2015 were included in a propensity score matching analysis. Only patients who underwent minimally invasive procedures for small HCC were included. Baseline clinical and laboratory parameters were retrieved from the hospital database and analyzed. Results: Two hundred and twenty-five patients underwent MIH or RFA for HCC during the study period. Propensity score matching yielded 59 patient-pairs. The complication rates did not differ statistically between the 2 groups (p = 0.309). However, MIH provided significantly better overall (p = 0.005) and disease-free survival outcomes (p < 0.001) than RFA. Conclusions: Compared with RFA, MIH provided better long-term survival outcomes in patients with early-stage HCC, with no increase in the incidence of complications. When feasible, MIH should be considered a first-line treatment for this patient population.
- Subjects
CATHETER ablation; MINIMALLY invasive procedures; HEPATOCELLULAR carcinoma; LAPAROSCOPIC surgery; HEPATECTOMY; PORTAL vein surgery
- Publication
Digestive Surgery, 2020, Vol 37, Issue 1, p65
- ISSN
0253-4886
- Publication type
Article
- DOI
10.1159/000497112